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首页> 外文期刊>Journal of Agricultural and Food Chemistry >Larvicidal Activity of the Active Constituent Isolated from Tabebuia avellanedae Bark and Structurally Related Derivatives against Three Mosquito Species
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Larvicidal Activity of the Active Constituent Isolated from Tabebuia avellanedae Bark and Structurally Related Derivatives against Three Mosquito Species

机译：分离自塔氏烟草（Tabebuia avellanedae）树皮的活性成分和结构相关衍生物对三种蚊虫的杀幼虫活性

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摘要

Mosquito larvicidal activities of active constituent isolated from Tabebuia avellanedae bark and its structurally related derivatives were examined against the fourth instar larvae of Aedes aegypti, Culex pipiens pallens, and Ochlerotatus togoi. The insecticidal constituent of T. avellanedae bark was isolated by chromatographic techniques and identified as 2-hydroxy-3-(3-methyl-2-butenyl)-l,4-naphthalenedione. On the basis of the 50% lethal concentration (LC_(50)) values against C pipiens pallens larvae, the most toxic compound was 1,4-naphthalenedione (1.26 mg/L), followed by 1,2-naphthalenedione (1.43 mg/L), 1,4-naphthalenediol (3.20 mg/L), 2-chloro-3-pyrrolidino-l,4-naphthalenedione (5.11 mg/L), 2-hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthalenedione (8.30 mg/L), and 2-chloro-3-morpholino-l,4-naphthalenedione (12.98 mg/L). Similar results against A. aegypti and 0. togoi larvae were observed for 2-hydroxy-3-(3-methyl-2-butenyI)-l,4-naphthaIenedione and its derivatives. According to the LC_(50) values against three mosquito species, these compounds were less toxic than pirimiphos-methyl. Nonetheless, naturally occurring T. avaellenedae bark-derived materials could be useful as a natural mosquito control agent.
机译：从伊蚊，埃及淡色库蚊和淡水古耳香椿的四龄幼虫中检测了从塔氏烟草（Tabebuia avellanedae）树皮及其结构相关衍生物中分离的活性成分的蚊虫幼虫活性。通过色谱技术分离了丁子香树皮的杀虫成分，并将其鉴定为2-羟基-3-（3-甲基-2-丁烯基）-1,4-萘二酮。根据淡色青色幼虫的50％致死浓度（LC_（50））值，毒性最高的化合物是1,4-萘二酮（1.26 mg / L），然后是1,2-萘二酮（1.43 mg / L） L），1,4-萘二醇（3.20 mg / L），2-氯-3-吡咯烷基-1,4-萘二酮（5.11 mg / L），2-羟基-3-（3-甲基-2-丁烯基） -1,4-萘二酮（8.30 mg / L）和2-氯-3-吗啉代-1,4-萘二酮（12.98 mg / L）。对于2-羟基-3-（3-甲基-2-丁烯基）-1，4-萘二酮及其衍生物，观察到针对埃及伊蚊和多哥0幼虫的相似结果。根据针对三种蚊虫的LC_（50）值，这些化合物的毒性小于丙胺磷。但是，天然存在的阿魏氏螺旋体树皮来源的材料可以用作天然的蚊子控制剂。

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