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首页> 外文期刊>Journal of Agricultural and Food Chemistry >Comment on Absorption of Aminoethyl Cysteine Ketimine Decarboxylated Dimer in Mice: Effect on Plasma Antioxidant Potential
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Comment on Absorption of Aminoethyl Cysteine Ketimine Decarboxylated Dimer in Mice: Effect on Plasma Antioxidant Potential

机译:氨基乙基半胱氨酸酮亚胺脱羧二聚体在小鼠中的吸收评论:对血浆抗氧化潜力的影响

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We wish to comment on a recent paper in this Journal by Piazzon et al. These authors supplemented the diet of experimental mice with 0.05 or 0.2% (w/w) aminoethylcysteine ketimine decarboxylated dimer (AECK-DD; systematic name 1,2-3,4-5,6-7,8-octahydro-1,8a-diaza-4,6-dithiafluoren-9(8aH)-one; Figure 1A) and noted the appearance of AECIC-DD in the plasma and liver in a time- and dose-dependent manner. Piazzon et al. reported plasma levels of AECK-DD of 39.7 ± 6.0 ng/mL (0.17 ± 0.03 μmol/L) and 126.0 ± 12.3 ng/mL (0.55 ± 0.05 μmol/L) in the mice supplemented with 0.05 and 0.2% AECK-DD in the diet for 24 h, respectively. These
机译:我们希望对Piazzon等人在本期刊上发表的一篇论文发表评论。这些作者用0.05或0.2%(w / w)氨乙基半胱氨酸酮亚胺脱羧二聚体(AECK-DD;系统名称1,2-3,4-5,6-7,8-octahydro-1,8a)补充了实验小鼠的饮食-diaza-4,6-dithiafluoren-9(8aH)-one;图1A),并注意到AECIC-DD在血浆和肝脏中的出现呈时间和剂量依赖性。 Piazzon等。补充了0.05和0.2%AECK-DD的小鼠的AECK-DD血浆水平分别为39.7±6.0 ng / mL(0.17±0.03μmol/ L)和126.0±12.3 ng / mL(0.55±0.05μmol/ L)饮食分别为24小时。这些

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