...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Agricultural and Food Chemistry >Limonoids from the Fruits of Aphanamixis polystachya (Meliaceae) and Their Biological Activities
【24h】

Limonoids from the Fruits of Aphanamixis polystachya (Meliaceae) and Their Biological Activities

机译：凤仙花果实中的柠檬苦素及其生物活性

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Seven new prieurianin-type limonoids, aphapolynins C-I (1-7), and a new aphanamolide-type limonoid, aphanamolide B (8), along with seventeen known compounds, were isolated from the fruits of Aphanamixis polystachya. The structures of these compounds were established on the basis of spectroscopic studies. The absolute configurations were determined by combination of electronic circular dichrpism (ECD) calculation, CD exciton chirality method, and single crystal X-ray diffraction. All these isolates were evaluated for their cytotoxicities against three human cancer cell lines, for their inhibitory effects on lipopolysaccharide (LPS) induced RAW264.7 murine macrophages, and for their fungicidal, herbicidal, and insecticidal activities. Compounds 1, 14, 16, and 17 exhibited significant fungicidal activities; 1 and 25 in particular showed good insecticidal activities. The α,β-unsaturated lactone and 14,15-epoxy ring moieties were essential for the insecticidal activity.
机译：从多香果树的果实中分离出了七个新的prieurianin型柠檬苦素，aphapolynins C-1（1-7）和一个新的瓜香酚类柠檬苦素，aphanamolide B（8），以及十七种已知化合物。这些化合物的结构是在光谱研究的基础上确定的。绝对构型是通过电子圆二色性（ECD）计算，CD激子手性法和单晶X射线衍射相结合来确定的。评价所有这些分离株对三种人类癌细胞系的细胞毒性，对脂多糖（LPS）诱导的RAW264.7鼠巨噬细胞的抑制作用以及其杀真菌，除草和杀虫活性。化合物1、14、16和17表现出显着的杀真菌活性。特别是图1和25显示出良好的杀虫活性。 α，β-不饱和内酯和14,15-环氧环部分对于杀虫活性至关重要。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号