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首页> 外文期刊>Journal of Agricultural and Food Chemistry >Nematicidal Activity of Natural Ester Compounds and Their Analogues against Pine Wood Nematode, Bursaphelenchus xylophilus
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Nematicidal Activity of Natural Ester Compounds and Their Analogues against Pine Wood Nematode, Bursaphelenchus xylophilus

机译：天然酯类化合物的杀线虫活性及其类似物对松材线虫Bursaphelenchus xylophilus的杀线作用

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摘要

In this study, we evaluated the nematicidal activity of natural ester compounds against the pine wood nematode, Bursaphelenchus xylophilus, to identify candidates for the development of novel, safe nematicides. We also tested the nematicidal activity of synthesized analogues of these ester compounds to determine the structure—activity relationship. Among 28 ester compounds tested, isobutyl 2-methylbutanoate, 3-methylbutyl 2-methylbutanoate, 3-methylbutyl tiglate, 3-methyl-2-butenyl % methylbutanoate, and pentyl 2-methylbutanoate showed strong nematicidal activity against the pine wood nematode at a 1 mg/ mL concentration. The other ester compounds showed weak nematicidal activity. The LC_(50) values of 3-methylbutyl tiglate, isobutyl 2-methylbutanoate, 3-methylbutyl 2-methylbutanoate, 3-methyl-2-butenyl 2-methylbutanoate, and pentyl 2-methylbutanoate were 0.0218, 0.0284, 0.0326, 0.0402, and 0.0480 mg/mL, respectively. The ester compounds described herein merit further study as potential nematicides for pine wood nematode control.
机译：在这项研究中，我们评估了天然酯化合物对松木线虫Bursaphelenchus xylophilus的杀线虫活性，以确定开发新型安全杀线虫剂的候选药物。我们还测试了这些酯化合物的合成类似物的杀线虫活性，以确定其结构活性关系。在测试的28种酯化合物中，2-甲基丁酸异丁酯，2-甲基丁酸3-甲基丁酯，钛酸3-甲基丁酯，3-甲基-2-丁烯基％甲基丁酸酯和2-甲基丁酸戊酯对松线虫的杀线虫活性为1 mg / mL浓度。其他酯化合物显示弱的杀线虫活性。钛酸3-甲基丁酯，2-甲基丁酸异丁酯，2-甲基丁酸3-甲基丁酯，2-甲基丁酸3-甲基-2-丁烯酯和2-甲基丁酸戊酯的LC_（50）值为0.0218、0.0284、0.0326、0.0402和分别为0.0480 mg / mL。本文所述的酯化合物作为用于控制松木线虫的潜在杀线虫剂值得进一步研究。

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