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首页> 外文期刊>Journal of Agricultural and Food Chemistry >Determination of Six Illegal Antibiotics in Chicken Jerky Dog Treats
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Determination of Six Illegal Antibiotics in Chicken Jerky Dog Treats

机译：鸡肉干狗零食中六种非法抗生素的测定

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In 2007 chicken jerky dog treats were implicated m causing illnesses and death in dogs in several countries Affected dogs were diagnosed with acquired Fancom syndrome, which is characterized by kidney malfunction Known causes of this condition include a chemical assault by various contaminants including certain drugs For this reason investigations into possible causes of the illnesses included antibiotics that may be used m animal husbandry Targeted analyte screens of individual imported chicken jerky dog treats using LC MS/MS detected six illegal antibiotics in imported products of several brands Trimethoprim, tilmicosm, enrofloxacin, sulfaclozme, and sulfamethoxazole are not allowed in chicken at any level and were found as high as 2800 ng/g (ppb) Sulfaqumoxaline was found m chicken jerky treats as high as 800 ng/g, which is well above the U S FDA tolerance of 100 ng/g Although there is no evidence these contaminants were responsible for the dog illnesses, their misuse could contribute to antibiotic resistant strains of bacteria
机译：2007年，在一些国家涉嫌鸡肉干狗零食，导致狗患病和死亡。受影响的狗被诊断出患有后天性Fancom综合征，其特征是肾功能不全。对引起疾病的可能原因进行的调查包括可能用于畜牧业的抗生素，使用LC MS / MS对个别进口的鸡肉干狗零食的目标分析物进行了筛查，在几种品牌的甲氧苄啶，替米莫司，恩诺沙星，磺胺氯辛，不允许在鸡肉中添加任何含量的二甲基亚砜和磺胺甲恶唑，且含量高达2800 ng / g（ppb）。在鸡肉干中发现的磺胺喹喔啉含量高达800 ng / g，远高于美国FDA的100 ng / g耐受性。 g尽管没有证据表明这些污染物是造成狗疾病的原因，但它们的滥用可能导致对细菌具有抗生素抗性的菌株

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