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首页> 外文期刊>Journal of Agricultural and Food Chemistry >Dietary Strategies To Reduce the Bioaccessibility of Arsenic from Food Matrices
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Dietary Strategies To Reduce the Bioaccessibility of Arsenic from Food Matrices

机译：减少食物基质中砷的生物可及性的饮食策略

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摘要

The main route of exposure to arsenic (As) is the consumption of water and foods, in which the forms with greatest toxicity are inorganic As and dimethylarsinic acid, DMA(V). The objective of this study was to search for dietary components that reduce the bioaccessibility of As from food and water, in order to reduce the amount of As available for absorption. For this purpose, 35 compounds were assayed by use of a static in vitro model of gastrointestinal digestion. Sulfates of Fe(II) and Fe(III) reduced the solubility of inorganic As (86-99%) and DMA(V) in aqueous solution (40-66%). This reduction was also observed in rice (100%) and seaweed (60%). Aluminum, titanium, and tannic acid also reduced the bioaccessibility of As from food (42-70%). These data show that the use of dietary components may be a good strategy to reduce the entry of As into systemic circulation.
机译：接触砷（As）的主要途径是水和食物的消耗，其中毒性最大的形式是无机砷和二甲基亚砷酸DMA（V）。这项研究的目的是寻找饮食成分，以减少食物和水中As的生物可及性，以减少可吸收的As量。为此，通过使用胃肠道消化的静态体外模型分析了35种化合物。 Fe（II）和Fe（III）的硫酸盐降低了无机As（86-99％）和DMA（V）在水溶液中的溶解度（40-66％）。在大米（100％）和海藻（60％）中也观察到这种减少。铝，钛和鞣酸还降低了食物中砷的生物可及性（42-70％）。这些数据表明，饮食成分的使用可能是减少砷进入全身循环的好策略。

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