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首页> 外文期刊>Journal of Applied Polymer Science >Improved Biocompatibility of Parylene-C Films Prepared by Chemical Vapor Deposition and the Subsequent Plasma Treatment
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Improved Biocompatibility of Parylene-C Films Prepared by Chemical Vapor Deposition and the Subsequent Plasma Treatment

机译：化学气相沉积和随后的等离子体处理所制备的聚对二甲苯-C薄膜的改善的生物相容性

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The purpose of this study is to prepare the thin film of C-type parylene (C-type polyxylylene, parylene- C) with improved biocompatibility for the biomedical applications, since in spite of the popularity, the parylene- C has been known to have the less biocompatibility than the N-type or D-type parylene. To prepare the welldesigned parylene films through the chemical vapor deposition (CVD) process and the subsequent plasma surface treatment, the parameters of deposition and surface modification were controlled to obtain optimized physical and surface properties. Using CVD, the thin films of parylene- C as thick as 5 lm were prepared under different deposition pressures. When increasing the deposition rate of parylene film or the deposition pressure, the tensile strength of film increased, whereas the properties such as the surface contact angle and permeability, and the elongation decreased. The deposition rate could be controlled to optimize the physical and physiochemical properties of films. The hydrophilicity of the parylene-C film increased after plasma surface treatment by showing the larger water contact angle than untreated one. When the radio frequency power was above 100 W in the plasma process, the thin film obtained reveals an excellent cytotropism. It shows the improved biocompatibility with living cells.
机译：这项研究的目的是制备具有改善的生物相容性的C型聚对二甲苯薄膜（C型聚对二甲苯，聚对二甲苯-C），用于生物医学应用，因为尽管众所周知，聚对二甲苯-C具有生物相容性比N型或D型聚对二甲苯低。为了通过化学气相沉积（CVD）工艺和随后的等离子体表面处理制备设计良好的聚对二甲苯膜，控制沉积和表面改性的参数以获得最佳的物理和表面性能。使用CVD，在不同的沉积压力下制备了厚达5 lm的聚对二甲苯-C薄膜。当增加聚对二甲苯膜的沉积速率或沉积压力时，膜的拉伸强度增加，而诸如表面接触角和磁导率的特性以及伸长率降低。可以控制沉积速率以优化膜的物理和物理化学性质。聚对二甲苯-C膜的亲水性在等离子表面处理后通过显示比未处理的更大的水接触角而增加。当在等离子体处理中射频功率高于100 W时，所获得的薄膜显示出优异的细胞趋向性。它显示出与活细胞的改善的生物相容性。

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