• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Applied Polymer Science >Empirical modeling development for integrated process optimization of poly(3-hydrxybutyrate-co-3-hydroxyvalerate) production
【24h】

Empirical modeling development for integrated process optimization of poly(3-hydrxybutyrate-co-3-hydroxyvalerate) production

机译：聚（3-羟基丁酸-co-3-羟基戊酸酯）生产的集成工艺优化的经验模型开发

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The optimization of P(3HB-co-3HV) synthesis was investigated using response surface methodology (RSM). Primary experiments showed different concentrations of 1-pentanol, agitation rates, and incubation times were the main factors influencing the production of this copolymer. To test the influence of the process parameters, two statistical experimental designs were performed. The first step of optimization used two-level factorial designs to determine the significant variables affecting the growth and production. The RSM model was experimentally validated yielding a maximum of 65 wt % PHA content and 10.2 g/L cell dry weight, which represent 12.1% increase in PHA content in comparison to the non-optimized condition using oleic acid and 1-pentanol as the carbon source and carbon precursor, respectively. The experimental results showed that the RSM was a useful tool as the utilization of 1-pentanol by Cupriavidus sp. USMAA2-4 was reduced by 33%. A second-order polynomial equation was obtained by multiple regression analysis to explain the combined effect of the three parameters with the coefficient of determination, R ~2, greater than 0.9. The optimum process conditions and interactions were determined by analyzing three-dimensional surfaces.
机译：P（3HB-co-3HV）合成的优化使用响应面方法（RSM）进行了研究。初步实验表明，不同浓度的1-戊醇，搅拌速率和孵育时间是影响该共聚物生产的主要因素。为了测试过程参数的影响，执行了两个统计实验设计。优化的第一步使用两级因子设计来确定影响生长和生产的重要变量。经过RSM模型的实验验证，最大PHA含量为65 wt％，细胞干重为10.2 g / L，与使用油酸和1-戊醇作为碳的非优化条件相比，PHA含量提高了12.1％。源和碳前体。实验结果表明，RSM是铜杯菌（Cupriavidus sp。）利用1-戊醇的有用工具。 USMAA2-4减少了33％。通过多元回归分析获得了二阶多项式方程，以解释这三个参数与确定系数R〜2大于0.9的组合作用。通过分析三维表面来确定最佳工艺条件和相互作用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号