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首页> 外文期刊>Journal of Applied Polymer Science >Fabrication of a poly(-caprolactone)/starch nanocomposite scaffold with a solvent-casting/salt-leaching technique for bone tissue engineering applications
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Fabrication of a poly(-caprolactone)/starch nanocomposite scaffold with a solvent-casting/salt-leaching technique for bone tissue engineering applications

机译：带有溶剂浇铸/盐浸技术的聚己内酯/淀粉纳米复合支架的制备，用于骨组织工程应用

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A series of nanocomposite scaffolds of poly(-caprolactone) (PCL) and starch with a range of porosity from 50 to 90% were fabricated with a solvent-casting/salt-leaching technique, and their physical and mechanical properties were investigated. X-ray diffraction patterns and Fourier transform infrared spectra confirmed the presence of the characteristic peaks of PCL in the fabricated scaffolds. Microstructure studies of the scaffolds revealed a uniform pore morphology and structure in all of the samples. The experimental measurements showed that the average contact angle of the PCL/starch composite was 88.05 +/- 1.77 degrees. All of the samples exhibited compressive stress/strain curves similar to those of polymeric foams. The samples with 50, 60, 70, and 80 wt % salt showed compressive-load-resisting capabilities in the range of human cancellous bone. With increasing porosity, a significant decrease in the mechanical properties of the scaffolds was observed. (c) 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016, 133, 43523.
机译：利用溶剂浇铸/盐浸技术制备了一系列聚（己内酯）（PCL）和淀粉的纳米复合支架，其孔隙率范围为50％至90％，并对其物理机械性能进行了研究。 X射线衍射图和傅立叶变换红外光谱证实了所制造的支架中PCL的特征峰的存在。支架的微观结构研究显示所有样品均具有均匀的孔形貌和结构。实验测量表明，PCL /淀粉复合材料的平均接触角为88.05 +/- 1.77度。所有样品均表现出类似于聚合物泡沫的压缩应力/应变曲线。含50、60、70和80 wt％盐的样品在人类松质骨范围内显示出抗压缩载荷的能力。随着孔隙率的增加，观察到支架的机械性能显着降低。 （c）2016 Wiley Periodicals，Inc. J. Appl。 Polym。科学2016，133，43523。

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