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Accurate determination of breast cancer size: The role of histopathology and imaging

机译：准确确定乳腺癌的大小：组织病理学和影像学的作用

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摘要

One critical role played by the pathologist in contemporary breast cancer management is that of providing accurate tumour measurements for staging and prognosis. Numerous factors have the potential to affect the final pathologist-recorded tumour size including diligence in measurement, tumour histology and growth pattern, tissue fixation and processing, prior biopsy and prior therapy. The pathologist should strive to provide three-dimensional tumour measurements in 0.1 cm increments from the gross specimen and then confirm these measurements microscopically whenever possible. In the era of breast conservation and emerging ablative therapies, the pathologist should also be familiar with the size-determining capability of various breast imaging techniques and their correlation with pathology. In determining final dimension, the pathologist is in a favourable position to verify or modify the size of a breast tumour based on the sum of information from all pathology specimens and, if appropriate, to correlate size with the patient's imaging studies.
机译：病理学家在当代乳腺癌治疗中扮演的关键角色之一是为分期和预后提供准确的肿瘤测量结果。许多因素都有可能影响最终病理学家记录的肿瘤大小，包括测量的努力，肿瘤组织学和生长方式，组织固定和处理，先前的活检和先前的治疗。病理学家应努力提供距大体标本0.1厘米的增量进行三维肿瘤测量，然后在可能的情况下用显微镜确认这些测量。在乳房保护和新兴消融治疗的时代，病理学家还应该熟悉各种乳房成像技术的尺寸确定能力及其与病理学的关系。在确定最终尺寸时，病理学家处于有利位置，可以根据所有病理标本的信息总和来验证或修改乳腺肿瘤的大小，并在适当的情况下将大小与患者的影像学研究相关联。

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