...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Neurophysiology >Changes in corticospinal excitability during reach adaptation in force fields
【24h】

Changes in corticospinal excitability during reach adaptation in force fields

机译：力场范围适应过程中皮质脊髓兴奋性的变化

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Both abrupt and gradually imposed perturbations produce adaptive changes in motor output, but the neural basis of adaptation may be distinct. Here, we measured the state of the primary motor cortex (M1) and the corticospinal network during adaptation by measuring motor-evoked potentials (MEPs) before reach onset using transcranial magnetic stimulation of M1. Subjects reached in a force field in a schedule in which the field was introduced either abruptly or gradually over many trials. In both groups, by end of the training, muscles that countered the perturbation in a given direction increased their activity during the reach (labeled as the on direction for each muscle). In the abrupt group, in the period before the reach toward the on direction, MEPs in these muscles also increased, suggesting a direction-specific increase in the excitability of the corticospinal network. However, in the gradual group, these MEP changes were missing. After training, there was a period of washout. The MEPs did not return to baseline. Rather, in the abrupt group, off direction MEPs increased to match on direction MEPs. Therefore, we observed changes in corticospinal excitability in the abrupt but not gradual condition. Abrupt training includes the repetition of motor commands, and repetition may be the key factor that produces this plasticity. Furthermore, washout did not return MEPs to baseline, suggesting that washout engaged a new network that masked but did not erase the effects of previous adaptation. Abrupt but not gradual training appears to induce changes in M1 and/or corticospinal networks. ? 2013 the American Physiological Society.
机译：突然的和逐渐施加的扰动都会在电机输出中产生适应性变化，但是适应的神经基础可能是不同的。在这里，我们通过经颅磁刺激M1来测量运动诱发电位（MEP），从而在适应过程中测量了主运动皮层（M1）和皮质脊髓网络的状态。受试者按时间表到达力场，在该时间表中，突然地或逐步地将力场引入许多试验中。在两组中，在训练结束时，在给定方向抵抗干扰的肌肉在活动范围内（标记为每条肌肉的开启方向）的活动都增加了。在突然的组中，在到达接通方向之前的时间段中，这些肌肉中的MEPs也增加了，表明皮质脊髓网络的兴奋性在特定方向上增加。但是，在渐进式组中，这些MEP更改丢失了。训练后，有一段时间的冲洗。欧洲议会议员没有回到基线。而是，在突然组中，偏向MEP增加到与偏向MEP相匹配。因此，我们观察到在突然但不是渐进的情况下皮质脊髓兴奋性的变化。突然的训练包括重复运动命令，重复可能是产生这种可塑性的关键因素。此外，冲洗不会使MEP恢复到基线，这表明冲洗参与了一个新的网络，该网络掩盖了但并未消除以前的适应效果。突然但非循序渐进的训练似乎会诱发M1和/或皮质脊髓网络的变化。 ？ 2013年美国生理学会。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号