DREADD-induced activation of subfornical organ neurons stimulates thirst and salt appetite

Haley L. Nation; Marvin Nicoleau; Brian J. Kinsman; Kirsteen N. Browning; Sean D. Stocker

首页> 外文期刊>Journal of Neurophysiology >DREADD-induced activation of subfornical organ neurons stimulates thirst and salt appetite

【24h】

DREADD-induced activation of subfornical organ neurons stimulates thirst and salt appetite

机译：DREADD诱导的下生殖器器官神经元激活刺激口渴和食欲

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Nation HL, Nicoleau M, Kinsman BJ, Browning KN, Stocker SD. DREADD-induced activation of subfornical organ neurons stimulates thirst and salt appetite. J Neurophysiol 115: 3123-3129, 2016. First published March 30, 2016; doi: 10.1152/jn.00149.2016.—The subfornical organ (SFO) plays a pivotal role in body fluid homeostasis through its ability to integrate neurohumoral signals and subsequently alter behavior, neuroendocrine function, and autonomic outflow. The purpose of the present study was to evaluate whether selective activation of SFO neurons using virally mediated expression of Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) stimulated thirst and salt appetite. Male C57BL/6 mice (12-15 wk) received an injection of rAAV2-CaMKH-HA-hM3D(Gq)-IRES-mCitrine targeted at the SFO. Two weeks later, acute

机译：Nation HL，Nicoleau M，Kinsman BJ，Browning KN，Stocker SD。 DREADD诱导的子器官下神经元的激活刺激了口渴和食欲。 J Neurophysiol 115：3123-3129，2016年。2016年3月30日首次发布。 doi：10.1152 / jn.00149.2016.—分支下器官（SFO）通过整合神经体液信号并随后改变行为，神经内分泌功能和自主神经流出的能力，在体液稳态中发挥关键作用。本研究的目的是评估使用由设计药物独家激活的设计受体的病毒介导表达选择性激活SFO神经元是否会刺激口渴和食欲。雄性C57BL / 6小鼠（12-15周）接受了针对SFO的rAAV2-CaMKH-HA-hM3D（Gq）-IRES-mCitrine注射液。两周后，急性

著录项

来源
《Journal of Neurophysiology》 |2016年第6期|共7页
作者
Haley L. Nation; Marvin Nicoleau; Brian J. Kinsman; Kirsteen N. Browning; Sean D. Stocker;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类
关键词

相似文献

外文文献
中文文献
专利

1. DREADD-induced activation of subfornical organ neurons stimulates thirst and salt appetite [J] . Haley L. Nation, Marvin Nicoleau, Brian J. Kinsman, Journal of Neurophysiology . 2016,第6期

机译：DREADD诱导的下生殖器器官神经元激活刺激口渴和食欲
2. Glutamate stimulation of arcuate nucleus inhibits responses of subfornical organ neurons to plasma hypernatremia and angiotensin II. [J] . Rosas Arellano MP, Solano Flores LP, Ciriello J Neuroscience Letters: An International Multidisciplinary Journal Devoted to the Rapid Publication of Basic Research in the Brain Sciences . 1995,第3期

机译：谷氨酸刺激弓形核抑制了子下器官神经元对血浆高钠血症和血管紧张素II的反应。
3. Hypocretin-1/orexin-A activates subfornical organ neurons of rats. [J] . Ono K, Kai A, Honda E, Neuroreport . 2008,第1期

机译：Hypocretin-1 / orexin-A激活大鼠的穹for下器官神经元。
4. Predicting the Stimulation Effectiveness Using Pre-stimulation Neural States via Optogenetic Activation of the Medial Septum Glutamatergic Neurons Modulating the Hippocampal Neural Activity [C] . Sang-Eon Park, Nealen G. Laxpati, Mark J. Connolly, Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2017

机译：通过致刺激神经状态通过神经外隔谷氨酸神经元调节海马神经活性的刺激神经状态来预测刺激效果
5. Tumor Necrosis Factor Alpha Influences the Excitability of Subfornical Organ Neurons and Potentiates Angiotensin II-Induced Calcium Activity [D] . Simpson, Nicholas. 2018

机译：肿瘤坏死因子α影响子下器官神经元的兴奋性并增强血管紧张素II诱导的钙活性。
6. DREADD-induced activation of subfornical organ neurons stimulates thirst and salt appetite [O] . Haley L. Nation, Marvin Nicoleau, Brian J. Kinsman, -1

机译：DREADD诱导的子生殖器官神经元激活刺激口渴和食欲不振
7. Distinct neural mechanisms for the control of thirst and salt appetite in the subfornical organ [O] . 松田隆志, マツダタカシ, Takashi MATSUDA 2017

机译：控制下颌器官口渴和食欲的独特神经机制

DREADD-induced activation of subfornical organ neurons stimulates thirst and salt appetite

摘要

著录项

相似文献

相关主题

期刊订阅