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Oxytocin and the Pharmacological Dissection of Affiliation

机译:催产素和隶属关系的药理学解剖

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摘要

Popularly hailed as the love hormone, oxytocin has emerged as a key variable in the regulation of human social cognition and behavior. In particular, research using intranasal oxytocin to pharmacologically manipulate the availability of oxytocin shows that oxytocin augmentation can promote a wide range of affiliative processes; however, evidence also shows null and even antisocial effects. Rather than random error to be eliminated, such variability may offer clues about the mechanisms by which oxytocin modulates human sociality. Three potential mechanismsanxiety reduction, social salience, and affiliative motivationare discussed, along with recent work showing how the affiliative-motivation hypothesis can simultaneously account for oxytocin's pro- and antisocial effects. Appreciating oxytocin's nuanced social effects is important for advancing our understanding of the neuroscience and psychology of affiliation.
机译:催产素被普遍称为爱情激素,已成为调节人类社会认知和行为的关键变量。特别是,使用鼻内催产素通过药理学控制催产素的有效性的研究表明,催产素的增加可以促进广泛的结合过程。然而,证据也显示出无效甚至反社会的影响。这种可变性可能会为催产素调节人类社交的机制提供线索,而不是消除随机误差。讨论了三种潜在的减少焦虑,社会显着性和亲和动机的机制,以及最近的工作表明亲和动机假说如何同时解释催产素的促社会和反社会作用。欣赏催产素细微的社会影响对于增进我们对隶属关系的神经科学和心理学的理解很重要。

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