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Processing in layer 4 of the neocortical circuit: new insights from visual and somatosensory cortex.

机译:在新皮层回路的第4层中进行处理:视觉和体感皮层的新见解。

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摘要

Recent experimental and theoretical results in cat primary visual cortex and in the whisker-barrel fields of rodent primary somatosensory cortex suggest common organizing principles for layer 4, the primary recipient of sensory input from the thalamus. Response tuning of layer 4 cells is largely determined by a local interplay of feed-forward excitation (directly from the thalamus) and inhibition (from layer 4 inhibitory interneurons driven by the thalamus). Feed-forward inhibition dominates excitation, inherits its tuning from the thalamic input, and sharpens the tuning of excitatory cells. Recurrent excitation enhances responses to effective stimuli.
机译:最近在猫的初级视觉皮层和啮齿动物的初级体感皮层的晶须区中的实验和理论结果表明,第4层(丘脑的感觉输入的主要接受者)的通用组织原理。第4层细胞的响应调节主要取决于前馈激发(直接来自丘脑)和抑制(来自丘脑驱动的第4层抑制性神经元)的局部相互作用。前馈抑制在激发中占主导地位,从丘脑输入继承其调谐,并增强兴奋性细胞的调谐。反复激发可增强对有效刺激的反应。

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