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Chemotherapy for trophoblastic disease: current standards.

机译:滋养细胞疾病的化学疗法:现行标准。

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Gestational trophoblastic diseases comprise a rare spectrum of disorders in which the normal regulatory mechanisms controlling the behaviour of trophoblastic tissue are lost. They vary from the benign complete and partial hydatidiform moles to the frankly malignant choriocarcinoma and placental site trophoblastic tumours. The majority will be cured by suction curettage, followed by human chorionic gonadotrophin screening, but some will go on to need chemotherapy. The majority of patients will be cured even despite the presence of metastatic disease. Patients should have their treatment stratified according to various prognostic factors in order to ensure firstly their disease is eliminated and secondly to reduce the incidence of long-term treatment complications.
机译:妊娠滋养细胞疾病包括罕见的疾病,其中失去了控制滋养细胞组织行为的正常调节机制。它们从良性的葡萄胎和部分葡萄胎到坦率的恶性绒毛膜癌和胎盘部位滋养细胞肿瘤不等。多数将通过刮宫术治愈,然后进行绒毛膜促性腺激素筛选,但有些将继续需要化疗。即使存在转移性疾病,大多数患者也可以治愈。患者应根据各种预后因素进行治疗分层,以确保首先消除疾病,其次减少长期治疗并发症的发生。

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