A gellan gum derivative as in-situ gelling cationic polymer for nasal drug delivery

Jelkmann Max; Leichner Christina; Zaichik Sergey; Laffleur Flavia; Bernkop-Schnuerch Andreas

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A gellan gum derivative as in-situ gelling cationic polymer for nasal drug delivery

机译：一种用于鼻药递送的原位胶凝阳离子聚合物的Gellan Gum衍生物

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摘要

The aim of the present study was the development of a novel gellan gum derivative exhibiting mucoadhesive properties for nasal application.

机译：本研究的目的是开发新的Gellan Gum衍生物，该衍生物表现出用于鼻腔应用的粘膜粘附性质。

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来源
《International Journal of Biological Macromolecules: Structure, Function and Interactions》 |2020年第1期|共10页
作者
Jelkmann Max; Leichner Christina; Zaichik Sergey; Laffleur Flavia; Bernkop-Schnuerch Andreas;
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作者单位

Univ Innsbruck Ctr Chem &

Biomed Inst Pharm Dept Pharmaceut Technol Innrain 80-82 A-6020 Innsbruck Austria;

Univ Innsbruck Ctr Chem &

Biomed Inst Pharm Dept Pharmaceut Technol Innrain 80-82 A-6020 Innsbruck Austria;

Univ Innsbruck Ctr Chem &

Biomed Inst Pharm Dept Pharmaceut Technol Innrain 80-82 A-6020 Innsbruck Austria;

Univ Innsbruck Ctr Chem &

Biomed Inst Pharm Dept Pharmaceut Technol Innrain 80-82 A-6020 Innsbruck Austria;

Univ Innsbruck Ctr Chem &

Biomed Inst Pharm Dept Pharmaceut Technol Innrain 80-82 A-6020 Innsbruck Austria;

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原文格式 PDF
正文语种 eng
中图分类生物大分子的结构和功能;
关键词
Nasal drug delivery; Polysaccharides; Aminated polymer; Mucoadhesion; in situ gelling;

机译：鼻药递送;多糖;胺化聚合物;粘膜粘附;原位胶凝;

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1. A gellan gum derivative as in-situ gelling cationic polymer for nasal drug delivery [J] . Jelkmann Max, Leichner Christina, Zaichik Sergey, International Journal of Biological Macromolecules: Structure, Function and Interactions . 2020,第1期

机译：一种用于鼻药递送的原位胶凝阳离子聚合物的Gellan Gum衍生物
2. Enhancement of Ocular In-Situ Gelling Properties of Low Acyl Gellan Gum by Use of Ion Exchange and Additional Polymers [J] . Reed Kenneth W., Li Amy, Fink Britney, Investigative ophthalmology & visual science . 2016,第12期

机译：通过使用离子交换和另外的聚合物增强低酰基胶囊胶的眼原位胶凝性质
3. A novel in situ gel base of deacetylase gellan gum for sustained ophthalmic drug delivery of ketotifen: in vitro and in vivo evaluation [J] . Lina Zhu, Junping Ao, Peiling Li Drug Design, Development and Therapy . 2015,第4期

机译：脱乙酰酶结冷胶的新型原位凝胶基质，用于酮替芬的眼科药物的持续眼部给药：体内外评价
4. Improving Transdermal Drug Delivery Using Gellan Gum Hydrogels and Temperature Responsive Nanospheres [C] . Carlos A. Carmona-Moran, Oleksandra Zavgorodnya, S. Louis Bridges Jr, Society for Biomaterials annual meeting and exposition . 2015

机译：使用结冷胶水凝胶和温度响应性纳米球改善透皮给药
5. The application of controlled radical polymerization processes on the graft copolymerization of hydrophobic substituents onto guar gum and guar gum derivatives. [D] . Holmes, Veronica K. 2007

机译：受控自由基聚合工艺在疏水取代基接枝共聚到瓜尔胶和瓜尔胶衍生物上的应用。
6. A novel in situ gel base of deacetylase gellan gum for sustained ophthalmic drug delivery of ketotifen: in vitro and in vivo evaluation [O] . Lina Zhu, Junping Ao, Peiling Li 2015

机译：脱乙酰酶结冷胶的新型原位凝胶基质用于酮替芬的眼科药物的持续眼部给药：体内和体外评估
7. A novel in situ gel base of deacetylase gellan gum for sustained ophthalmic drug delivery of ketotifen: in vitro and in vivo evaluation [O] . Peiling Li, Lina Zhu, Junping Ao 2015

机译：一种新的脱乙酰酶Gellan Gul Gellan Gul碱基的新型眼科药物递送KetotIfen：体外和体内评价

A gellan gum derivative as in-situ gelling cationic polymer for nasal drug delivery

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