No protection of heart, kidneys and brain by remote ischemic preconditioning before transfemoral transcatheter aortic valve implantation: Interim-analysis of a randomized single-blinded, placebo-controlled, single-center trial

Kahlert Philipp; Hildebrandt Heike Annelie; Patsalis Polykarpos Christos; Al-Rashid Fadi; Janosi Rolf Alexander; Nensa Felix; Schlosser Thomas Wilfried; Schlamann Marc; Wendt Daniel; Thielmann Matthias; Kottenberg Eva; Frey Ulrich; Neuhaeuser Markus; Forsting Michael; Jakob Heinz Guenther; Rassaf Tienush; Peters Juergen; Heusch Gerd; Kleinbongard Petra

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No protection of heart, kidneys and brain by remote ischemic preconditioning before transfemoral transcatheter aortic valve implantation: Interim-analysis of a randomized single-blinded, placebo-controlled, single-center trial

机译：通过在经变压器主动脉瓣植入前的远程缺血预处理无保护心脏，肾脏和大脑：随机单盲，安慰剂控制，单中心试验的中期分析

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Background: Remote ischemic preconditioning (RIPC) reduces myocardial injury and improves clinical outcome in patients undergoing coronary revascularization, but only in the absence of propofol-anesthesia. We investigated whether RIPC provides protection of heart, kidneys and brain and improves outcome in patients undergoing transfemoral transcatheter aortic valve implantation (TF-TAVI).

机译：背景：远程缺血预处理（RIPC）可降低心肌损伤，并提高冠状动脉血运重建患者的临床结果，但仅在没有异丙酚麻醉的情况下。我们调查了RIPC是否提供了心脏，肾脏和脑的保护，并改善了经过血换转膜管主动脉瓣膜植入（TF-Tavi）的患者的结果。

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来源
《International Journal of Cardiology》 |2017年第2017期|共7页
作者
Kahlert Philipp; Hildebrandt Heike Annelie; Patsalis Polykarpos Christos; Al-Rashid Fadi; Janosi Rolf Alexander; Nensa Felix; Schlosser Thomas Wilfried; Schlamann Marc; Wendt Daniel; Thielmann Matthias; Kottenberg Eva; Frey Ulrich; Neuhaeuser Markus; Forsting Michael; Jakob Heinz Guenther; Rassaf Tienush; Peters Juergen; Heusch Gerd; Kleinbongard Petra;
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作者单位

Univ Duisburg Essen Univ Klinikum Essen West German Heart &

Vasc Ctr Essen Dept Cardiol &

Vasc;

Univ Duisburg Essen Univ Klinikum Essen West German Heart &

Vasc Ctr Essen Dept Cardiol &

Vasc;

Univ Duisburg Essen Univ Klinikum Essen West German Heart &

Vasc Ctr Essen Dept Cardiol &

Vasc;

Univ Duisburg Essen Univ Klinikum Essen West German Heart &

Vasc Ctr Essen Dept Cardiol &

Vasc;

Univ Duisburg Essen Univ Klinikum Essen West German Heart &

Vasc Ctr Essen Dept Cardiol &

Vasc;

Univ Duisburg Essen Univ Klinikum Essen Inst Diagnost &

Intervent Radiol &

Neuroradiol Duisburg;

Univ Duisburg Essen Univ Klinikum Essen Inst Diagnost &

Intervent Radiol &

Neuroradiol Duisburg;

Univ Duisburg Essen Univ Klinikum Essen Inst Diagnost &

Intervent Radiol &

Neuroradiol Duisburg;

Univ Duisburg Essen Univ Klinikum Essen West German Heart &

Vasc Ctr Essen Dept Thorac &

Univ Duisburg Essen Univ Klinikum Essen West German Heart &

Vasc Ctr Essen Dept Thorac &

Univ Duisburg Essen Univ Klinikum Essen Klin Anasthesiol &

Intensivmed Duisburg Germany;

Univ Duisburg Essen Univ Klinikum Essen Klin Anasthesiol &

Intensivmed Duisburg Germany;

Univ Duisburg Essen Univ Klinikum Essen Inst Med Informat Biometry &

Epidemiol Duisburg Germany;

Univ Duisburg Essen Univ Klinikum Essen Inst Diagnost &

Intervent Radiol &

Neuroradiol Duisburg;

Univ Duisburg Essen Univ Klinikum Essen West German Heart &

Vasc Ctr Essen Dept Thorac &

Univ Duisburg Essen Univ Klinikum Essen West German Heart &

Vasc Ctr Essen Dept Cardiol &

Vasc;

Univ Duisburg Essen Univ Klinikum Essen Klin Anasthesiol &

Intensivmed Duisburg Germany;

Univ Duisburg Essen Univ Klinikum Essen West German Heart &

Vasc Ctr Essen Inst Pathophysiol;

Univ Duisburg Essen Univ Klinikum Essen West German Heart &

Vasc Ctr Essen Inst Pathophysiol;

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原文格式 PDF
正文语种 eng
中图分类心脏、血管（循环系）疾病;
关键词
Brain; Cardioprotection; Heart; Kidney; RIPC; TAVI;

机译：大脑;心脏保护;心脏;肾脏;RIPC;TAVI;

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1. No protection of heart, kidneys and brain by remote ischemic preconditioning before transfemoral transcatheter aortic valve implantation: Interim-analysis of a randomized single-blinded, placebo-controlled, single-center trial [J] . Kahlert Philipp, Hildebrandt Heike Annelie, Patsalis Polykarpos Christos, International Journal of Cardiology . 2017,第期

机译：通过在经变压器主动脉瓣植入前的远程缺血预处理无保护心脏，肾脏和大脑：随机单盲，安慰剂控制，单中心试验的中期分析
2. Effect of a Cerebral Protection Device on Brain Lesions Following Transcatheter Aortic Valve Implantation in Patients With Severe Aortic Stenosis The CLEAN-TAVI Randomized Clinical Trial [J] . Haussig Stephan, Mangner Norman, Dwyer Michael G., JAMA: the Journal of the American Medical Association . 2016,第6期

机译：重度主动脉瓣狭窄患者脑保护装置对经导管主动脉瓣植入后脑部病变的影响CLEAN-TAVI随机临床试验
3. Effect of a Cerebral Protection Device on Brain Lesions Following Transcatheter Aortic Valve Implantation in Patients With Severe Aortic Stenosis The CLEAN-TAVI Randomized Clinical Trial [J] . Haussig Stephan, Mangner Norman, Dwyer Michael G., JAMA: the Journal of the American Medical Association . 2016,第6期

机译：重度主动脉瓣狭窄患者脑保护装置对经导管主动脉瓣植入后脑部病变的影响CLEAN-TAVI随机临床试验
4. Using Clinical Decision Support and Dashboard Technology to Improve Heart Team Efficiency and Accuracy in a Transcatheter Aortic Valve Implantation (TAVI) Program [C] . Sarah CLARKE MSN, Marisa L. WILSON, Mary TERHAAR International Congress in Nursing Informatics . 2016

机译：采用临床决策支持和仪表板技术，提高经齿轮机主动脉瓣植入（TAVI）计划中的心脏团队效率和准确性
5. Transcatheter aortic valve implantation: Does cerebral protection decrease cerebral ischemia? [D] . Haber, Benjamin. 2013

机译：经导管主动脉瓣植入术：脑保护可减少脑缺血吗？
6. Remote Ischemic Preconditioning Neither Improves Survival nor Reduces Myocardial or Kidney Injury in Patients Undergoing Transcatheter Aortic Valve Implantation (TAVI) [O] . Mandy Flechsig, Tobias F. Ruf, Willi Troeger, 2020

机译：经导管主动脉瓣植入术（TAVI）的患者远程缺血预处理既不能提高生存率也不能减少其对心肌或肾脏的伤害
7. P1246Age-, body size-, and sex-specific reference values for tricuspid valve apparatus parameters by real-time three-dimensional transthoracic echocardiographyP1247Surgical therapy in infective endocarditis: predisposing and prognostic factorsP1248Evalutation of MV annulus geometry modifications before and after mitraclip implantation with 3D transesophageal echocardiographyP1249Prognostic echocardiographic parameters for successful transcatheter edge-to-edge mitral valve repairP1250Influence of body surface area in diagnosis and outcome patient-prosthesis mismatch after TAVI. Is it necessary to adjust for ideal body weight?P1251Outcome of paradoxical low-flow low-gradient severe AS following TAVI: paradoxical VS parallel to outcome of high gradient ASP1252Prognostic role of cardiac calcifications in subjects without overt significant heart disease and previous cardiovascular events: is there an additive value over cardiovascular risk factors scores?P1253Aging degeneration of mitral valve without leaflet prolapse or tethering as a cause of severe mitral regurgitationP1254Cardiovascular risk assessment should be performed in patients with incidental aortic sclerosisP1255Cardiac valve calcification score: simple 2D echocardiographic tool for cardiovascular risk stratification in patients with chronic renal failureP1256Diastolic mitral regurgitation following transcatheter aortic valve replacement: prevalence, predictors and impact on outcomesP1257Timing of myocardial shortening determines left ventricular regional remodelling in hearts with conduction delaysP1258Myocardial stiffness assessment using shear wave imaging in healthy children and hypertrophic cardiomyopathyP1259Assessment of right ventricular response to exercise using vector velocity imaging in hypertrophic cardiomyopathyP1260Diagnostic value of cardiac biomarkers (high sensitive troponin T and N-terminal pro-brain natriuretic peptide) in patients with infiltrative cardiomyopathiesP1261Right ventricular global longitudinal strain differentiates between adolescent patients with definite, borderline and possible ARVC and controlsP1262 echogrqphic predictif factors of atrial arrhythmias in patients with arrhythmogenic right ventricular dysplasiaP1263Importance of combined left atrial size and estimated pulmonary pressure for clinical outcome in patients presenting with heart failure with preserved ejection fractionP1264Chronotropic response in mitochondrial (ANT1) cardiomyopathyP1265 The effect of cardiovascular risk factors and cancer type in anthracycline's cardiotoxicityP1266Revisiting the echocardiographic features of acute myocarditisP1267Altered circulation in fetuses of diabetic mothers: a fetal computational model analysisP1268Increased epicardial adipose tissue is related to stress-induced cardiomyopathyP1269Contrast enhanced ultrasound of kidney perfusion in patients with renal artery stenosis: diagnostic and prognostic applications. [O] . F. Ancona, R. Ilhao Moreira, V. Lavanco, 2016

机译：P1246age-，身体大小和性别特异性参考Tricuspid阀装置参数通过实时三维经线性超声心动图124772777777747774747478EVALIGUTALMEXP1249预期植入前后MV环形植入前后MV环空性修饰。超声心动图参数用于成功的经截管边缘到边缘二尖瓣修复P1250中的体表面积诊断和结果患者假体在Tavi后的不匹配。是否有必要调整理想的体重？P1251矛盾的低流量低梯度严重，如Tavi：矛盾的VS平行于高梯度ASP1252的结果，在没有明显显着的心脏病和以前心血管事件的情况下心脏钙化的促傲作用患有心血管危险因素的添加剂值分数？没有传单脱垂的二尖瓣退化或作为严重二尖瓣血管血管血管病风险评估的患者进行脱垂或系绳，应当在偶然主动脉源肺源P1255Cariac阀钙化评分患者中进行：用于心血管风险分层的简单2D超声心动图工具在慢性肾功能衰竭的患者中，经沟管主动脉瓣膜置换术后：流行率，预测因子和对Otcomasp1257的影响，心肌缩短决定了导通延迟的心中的剩余心室区域重新耦合258MYCIARIAL僵硬评估使用剪切波成像在健康儿童和肥厚性心肌脑病中的舒缓性心脏响应，在渗透心肌肌瘤患者中使用载体速度成像的培养速度成像（高敏感的肌钙蛋白T和N-末端脑Natrietic肽）渗透心肌病，患者心室全局纵向菌株在患有心律失常右心室发育不良患者的心理心律失常患者中的青少年患者与Controlsp1262 echogrqphic预测因子的分歧，患者心血性右心室发育不良患者患者患者患者患者患者患者患者患者患者线粒体（ANT1）心肌病患者的喷射FRACTIONP1264系列响应1265心血管危险因素和癌症类型在蒽丙烯的心肌毒性皮1126660中的影响访问患有糖尿病母亲胎儿胎儿急性心肌炎的超声心动图，患者患者：胎儿计算模型分析P1268增加外膜脂肪组织与肾动脉狭窄患者肾脏灌注的应激诱导的心肌病，增强超声波：诊断和预后应用。

No protection of heart, kidneys and brain by remote ischemic preconditioning before transfemoral transcatheter aortic valve implantation: Interim-analysis of a randomized single-blinded, placebo-controlled, single-center trial

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