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首页> 外文期刊>Forest Ecology and Management >Preemptive Analgesia, Including Morphine, Does Not Affect Recovery Quality and Times in Either Pain-Free Horses or Horses Undergoing Orchiectomy
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Preemptive Analgesia, Including Morphine, Does Not Affect Recovery Quality and Times in Either Pain-Free Horses or Horses Undergoing Orchiectomy

机译：包括吗啡，包括吗啡的先发型镇痛不会影响锻造术的无痛苦的马匹或马匹中的恢复质量和时间

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Recovery quality and times from general anesthesia in horses may be influenced by surgery, analgesia with morphine or combinations of both. Twenty-three adult healthy horses were enrolled in this prospective experimental trial in a clinical setting and were randomly allocated to one of the following groups: anesthesia only (GA; n = 6), preemptive analgesia and anesthesia (GAA; n = 5), anesthesia and castration (GC; n = 6), or preemptive analgesia, anesthesia, castration, and intraoperative local analgesia (GCA; n = 6). All horses were sedated with intramuscular (IM) xylazine (0.5 mg/kg). Anesthesia was induced with intravenous (IV) guaifenesin (100 mg/kg) and thiopental (5 mg/kg) and maintained with isoflurane in oxygen. Animals in groups with preemptive analgesia received IM morphine (0.2 mg/kg) and dipyrone (10 mg/kg) and IV flunixin meglumine (1.0 mg/kg) immediately before sedation. Recoveries from general anesthesia were rope -assisted. Recovery scores (from 8 [excellent recovery] to 70 [worst recovery]) and times were compared between groups, using a one-way analysis of variance followed by a Tukey's test (P .05). Mean standard deviation (SD) and range recovery scores were 22 +/- 14 (8-45), 9 +/- 2 (8-12), 14 +/- 5 (8-22), and 12 +/- 1 (10-13) in groups GA, GAA, GC, and GCA, respectively. Mean +/- SD times to stand in minutes were 21 +/- 10,18 +/- 7, 33 +/- 12, and 35 +/- 21 in groups GA, GAA, GC and GCA, respectively. No statistically significant differences were found for any of the variables. Neither preoperative administration of analgesics, including morphine, nor castration interfered with the recovery qualities and times in horses undergoing general anesthesia. Preemptive morphine did not worsen anesthetic recovery quality in horses. (C) 2016 Elsevier Inc. All rights reserved.
机译：从马匹中全身麻醉的恢复质量和时间可能受到手术，镇痛的影响，与吗啡或两者的组合。在临床环境中注册了二十三名成人健康的马匹，随机分配给以下群体之一：仅仅（Ga; n = 6），先发制人镇痛和麻醉（Gaa; n = 5），麻醉和阉割（GC; N = 6），或先发制人的镇痛，麻醉，阉割和术中局部镇痛（GCA; n = 6）。所有的马镇静用肌内（IM）木嗪（0.5mg / kg）。用静脉注射（IV）Guaifenesin（100mg / kg）和硫喷妥（5mg / kg）诱导麻醉，并在氧中维持异氟醚。在镇静前立即接受血髓镇痛的血液镇痛的群体和二酪酮（10mg / kg）和静脉霉素（1.0mg / kg）。来自全身麻醉的回收率是绳子 - 归档。在组之间使用单向分析跟随Tukey的测试（P <.05）之间比较恢复分数（从8 [最优秀的恢复]到70 [最糟糕的恢复]）和时间。平均标准偏差（SD）和范围恢复评分为22 +/- 14（8-45），9 +/- 2（8-12），14 +/- 5（8-22）和12 +/- 1 （10-13）分别在Ga，Gaa，GC和GCA中。平均+/- SD次数分钟分别为21 +/- 10,18 +/- 7,33 +/- 12和35 +/- 21分别为GA，Gaa，GC和GCA。对于任何变量，没有发现统计学上的显着差异。既不是术前施用镇痛药，包括吗啡，也不干扰了经历过全身麻醉的马匹中的恢复品质和时期。先发制人的吗啡在马中没有恶化麻醉恢复品质。 （c）2016 Elsevier Inc.保留所有权利。

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