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Synthesis of bifunctional carbon quantum dots for bioimaging and anti-inflammation

机译:双官能碳量子点的生物分析和抗炎的合成

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Carbon quantum dots (CDs) have attracted increased attention in recent decades because of their various applications in biosensing, bioimaging and drug delivery. In the present study, we have synthesized bifunctional ibuprofen-based carbon quantum dots (ICDs) using a simple one-step microwave-assisted method, for simultaneous bioimaging and anti-inflammatory effects. The ICDs exhibited high stability, low toxicity, negligible cytotoxicity and good biocompatibility in water. In particular, the produced ICDs demonstrated a decent imaging ability and excellent anti-inflammatory effects in vivo, making them potentially useful in bioimaging and future clinical treatment. Our results demonstrated that ICDs show promise in applications such as multifunctional biomaterials, depending on the selection of carbon sources, which would provide important guidance for the future design of multifunctional CDs in the field of biomedicine.
机译:由于生物传感,生物体和药物递送的各种应用,近几十年来,碳量子点(CDS)引起了更多的关注。 在本研究中,我们使用简单的一步微波辅助方法合成基于双官能的布洛芬的碳量子点(ICDS),用于同时消影和抗炎作用。 ICD表现出高稳定性,低毒性,细胞毒性可忽略不计的细胞毒性和水中良好的生物相容性。 特别是,所生产的ICD证明了体内体内的体面的成像能力和优异的抗炎作用,使它们可能在生物体和未来的临床治疗中有用。 我们的研究结果表明,ICDS在多功能生物材料等应用中显示了许可,这取决于碳源的选择,这将为生物医学领域的多功能CD设计提供重要指导。

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