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Soft nanostructured films for directing the assembly of functional materials

机译：用于指导功能材料组装的软纳米结构薄膜

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摘要

Lipids are a class of biological small molecules with hydrophilic and hydrophobic constituents forming the structural membranes in cells. Over the past century an extensive understanding of lipid biology and biophysics has been developed illuminating lipids as an intricate, highly tunable, and hierarchical soft-matter system. In addition to serving as cell membrane models, lipids have been investigated as microphase separated structures in aqueous solutions. In terms of applications lipids have been realized as powerful structural motifs for the encapsulation and cellular delivery of genetic material. More recently, lipids have also revealed promise as thin film materials, exhibiting long-range periodic nano-scale order and tunable orientation. In this review we summarize the pertinent understanding of lipid nanostructure development in bulk aqueous systems followed by the current and potential perturbations to these results induced by introduction of a substrate. These effects are punctuated by a summary of our published results in the field of lipid thin films with added nucleic acids and key results introducing hard materials into lipid nanostructured substrates.
机译：脂质是一类具有亲水和疏水成分的生物小分子，形成细胞中的结构膜。在过去的一世纪中，对脂质生物学和生物物理学的广泛理解已经开发出脂质作为复杂，高度可调和等级柔软的物质系统。除了用作细胞膜模型之外，已经研究了脂质作为水溶液中的微生物分离结构。就应用而言，脂质已经实现为遗传物质的包封和细胞递送的强大结构基序。最近，脂质也揭示了承诺作为薄膜材料，表现出远程周期性纳米级顺序和可调定向。在本次综述中，我们总结了对散装水性系统中的脂质纳米结构发育的相关理解，然后通过引入基材引起这些结果的电流和潜在扰动。这些效应通过我们公开的结果的概要来调分，在脂质薄膜领域，添加核酸和关键结果将硬质材料引入脂质纳米结构的基材。

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