首页> 外文期刊>Nanotechnology >Zeolitic imidazolate framework-8 (ZIF-8) as a sacrificial template: one-pot synthesis of hollow poly(dopamine) nanocapsules and yolk-structured poly(dopamine) nanocomposites
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Zeolitic imidazolate framework-8 (ZIF-8) as a sacrificial template: one-pot synthesis of hollow poly(dopamine) nanocapsules and yolk-structured poly(dopamine) nanocomposites

机译:Zeolital Imidazolate框架-8(ZIF-8)作为牺牲模板:中空聚(多巴胺)纳米胶囊和蛋黄结构聚(多巴胺)纳米复合材料的单罐合成

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摘要

Hollow poly(dopamine) (PDA) nanocapsules and yolk-structured PDA nanocomposites were prepared by an aqueous one-pot synthesis method utilizing zeolitic imidazolate framework-8 (ZIF-8) nanocrystals as a sacrificial template without any special etchant. The resulting PDA nanocapsules show negligible cytotoxicity in HeLa cells after incubation for 48 h at various doses, which implies their potential as candidates for practical applications in drug transport and targeting.
机译:中空聚(多巴胺)(PDA)纳米腐植物和蛋黄结构化PDA纳米复合材料通过单盆性合成方法制备,其利用沸石咪唑酯框架-8(ZIF-8)纳米晶体作为牺牲模板而没有任何特殊蚀刻剂。 所得PDA纳米胶囊以各种剂量孵育48小时后,HeLa细胞中的细胞毒性可忽略不计细胞毒性,这意味着它们作为药物运输和靶向的实际应用的候选者的潜力。

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