Palladium-catalyzed three-component reaction for the synthesis of 3,3-disubstituted allylic alcohols with regio- and stereoselectivity

Hu Gang; Wang Jingtao; Li Zefei; Liu Yajing; Gong Ping

首页> 外文期刊>New Journal of Chemistry >Palladium-catalyzed three-component reaction for the synthesis of 3,3-disubstituted allylic alcohols with regio- and stereoselectivity

【24h】

Palladium-catalyzed three-component reaction for the synthesis of 3,3-disubstituted allylic alcohols with regio- and stereoselectivity

机译：钯催化的三分组分反应，用于合成3,3-二取代的烯丙基醇，具有测定和立体选择性

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

A novel three-component assembly of allenic alcohols, aryl iodides and 1,3-dicarbonyl compounds into 3,3-disubstituted allylic alcohols was promoted in the presence of a palladium source. A plausible mechanism through Pd-0 catalysis was established to explain the regio- and stereoselectivity. Various aryl iodides and functionalized dicarbonyls were well-tolerated to afford products in good to moderate yields.

机译：在钯源的存在下促进了甲烷醇，芳基碘化物，1,3-二羰基化合物的三种三组分组装成3,3-二二烷基醇。建立了通过PD-0催化的合理机制来解释序列和立体选择性。良好耐受各种芳基碘和官能化的二羰基，得到良好的产物至中等产率。

著录项

来源
《New Journal of Chemistry》 |2018年第3期|共4页
作者
Hu Gang; Wang Jingtao; Li Zefei; Liu Yajing; Gong Ping;
展开▼
作者单位

Shenyang Pharmaceut Univ Minist Educ Key Lab Struct Based Drug Design &

Discovery 103 Wenhua Rd Shenyang 110016 Liaoning Peoples R China;

Shenyang Pharmaceut Univ Minist Educ Key Lab Struct Based Drug Design &

Discovery 103 Wenhua Rd Shenyang 110016 Liaoning Peoples R China;

Shenyang Pharmaceut Univ Minist Educ Key Lab Struct Based Drug Design &

Discovery 103 Wenhua Rd Shenyang 110016 Liaoning Peoples R China;

Shenyang Pharmaceut Univ Minist Educ Key Lab Struct Based Drug Design &

Discovery 103 Wenhua Rd Shenyang 110016 Liaoning Peoples R China;

Shenyang Pharmaceut Univ Minist Educ Key Lab Struct Based Drug Design &

Discovery 103 Wenhua Rd Shenyang 110016 Liaoning Peoples R China;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类化学;
关键词

相似文献

外文文献
中文文献
专利

1. Palladium-catalyzed three-component reaction for the synthesis of 3,3-disubstituted allylic alcohols with regio- and stereoselectivity [J] . Hu Gang, Wang Jingtao, Li Zefei, New Journal of Chemistry . 2018,第3期

机译：钯催化的三分组分反应，用于合成3,3-二取代的烯丙基醇，具有测定和立体选择性
2. Regio- and stereoselective synthesis of functionalized allylic fluorides via palladium-catalyzed three-component tandem carbofluorination of allenes [J] . Liu Shasha, Zhao Jinbo, Zhang Ge Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry . 2015,第17期

机译：通过钯催化的三烯串联碳氟化反应区域和立体选择性合成功能化的烯丙基氟化物
3. Regio- and Stereoselective Synthesis of Multi-Alkylated Allylic Boronates through Three-Component Coupling Reactions between Allenes, Alkyl Halides, and a Diboron Reagent [J] . Yu Ozawa, Kohei Endo, Hajime Ito Journal of the American Chemical Society . 2021,第34期

机译：通过甲烷，烷基卤化物和二硼试剂之间的三组分偶联反应的多烷基化烯丙基硼酸盐的测定和立体选择性合成
4. Stereoselective Synthesis of δ-Silyl-Substituted anti-Homoallylic Alcohols Using Palladium-Catalyzed Three-Component Reaction [C] . MURAKAMI Miki, HORINO Yoshikazu, ABE Hitoshi 日本化学会春季年会講演予稿集 . 2018

机译：使用钯催化的三组分反应的δ-甲硅烷基取代的抗官能醇的立体选择性合成
5. Asymmetric synthesis of all-carbon alpha-aryl quaternary carbonyl compounds by palladium-catalyzed asymmetric allylic alkylation (Pd-AAA) and their application to the synthesis of biologically important 3,3 '-disubstituted oxindole and alpha-disubstituted quaternary beta-lactone frameworks. [D] . Asad, Md. Sharif A. 2015

机译：钯催化的不对称烯丙基烷基化反应（Pd-AAA）的全碳α-芳基季羰基化合物的不对称合成及其在生物学上重要的3,3'-二取代的羟吲哚和α-二取代的季铵β-内酯骨架的合成中。
6. Stereoselective Synthesis of cis- or trans-35-Disubstituted Pyrazolidines via Pd-Catalyzed Carboamination Reactions. Use of Allylic Strain to Control Product Stereochemistry Through N-Substituent Manipulation [O] . Natalie C. Giampietro, John P. Wolfe -1

机译：通过Pd催化的碳氨化反应立体选择性地合成顺式或反式35-二取代的吡唑烷。使用烯丙基菌株通过N取代基操纵来控制产物立体化学
7. Palladium-mediated highly regio- and stereoselective intermolecular β-arylation on allylic alcohols: Synthesis of functionalized allylic alcohols [O] . J Krishna, A Gopi Krishna Reddy, B Venkat Ramulu, 2012

机译：钯介导的烯丙基醇上的高度区域和立体选择性分子间β-芳基化反应：官能化烯丙基醇的合成

Palladium-catalyzed three-component reaction for the synthesis of 3,3-disubstituted allylic alcohols with regio- and stereoselectivity

摘要

著录项

相似文献

相关主题

期刊订阅