Hyptis verticillata attenuates dyslipidaemia, oxidative stress and hepato-renal damage in streptozotocin-induced diabetic rats

Ogar Ironya; Egbung Godwin Eneji; Nna Victor Udo; Atangwho Item Justin; Itam Edisua Hogan

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Hyptis verticillata attenuates dyslipidaemia, oxidative stress and hepato-renal damage in streptozotocin-induced diabetic rats

机译：Hyptis Verticillata在链脲佐菌素诱导的糖尿病大鼠中衰减血脂血症，氧化应激和肝肾损伤

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Aims: Chronic hyperglycaemia in diabetes mellitus (DM) increases the production of free radicals which results in oxidative stress and related disorders such as cardiovascular diseases, compromised hepatic and renal functions. Hyptis verticillata reportedly demonstrated glucose lowering activity in previous studies. The present study therefore evaluated the effect of H. verticillata on hyperglycaemia-induced dyslipidaemia, hepatorenal distortions, oxidative stress, as well as calculated indices of cardiovascular function.

机译：目的：糖尿病（DM）的慢性高血糖可增加自由基的产生，导致氧化应激和相关疾病，如心血管疾病，受损的肝癌和肾功能。据报道，Hyptis Verticillata在先前的研究中表明葡萄糖降低活性。因此，本研究评估了H. Verticillata对高血糖诱导的血脂血症，肝癌畸变，氧化应激以及计算的心血管功能指标的影响。

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来源
《Life sciences》 |2019年第2019期|共11页
作者
Ogar Ironya; Egbung Godwin Eneji; Nna Victor Udo; Atangwho Item Justin; Itam Edisua Hogan;
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作者单位

Univ Calabar Dept Biochem Coll Med Sci PMB 1115 Calabar Cross River Sta Nigeria;

Univ Calabar Dept Biochem Coll Med Sci PMB 1115 Calabar Cross River Sta Nigeria;

Univ Calabar Dept Physiol Coll Med Sci PMB 1115 Calabar Cross River Sta Nigeria;

Univ Calabar Dept Biochem Coll Med Sci PMB 1115 Calabar Cross River Sta Nigeria;

Univ Calabar Dept Biochem Coll Med Sci PMB 1115 Calabar Cross River Sta Nigeria;

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原文格式 PDF
正文语种 eng
中图分类医药、卫生;
关键词
Diabetes mellitus; Hyptis verticillata; Oxidative stress; Antioxidant; Hepato-renal lesion;

机译：糖尿病;Hyptis Verticillata;氧化应激;抗氧化剂;肝肾病变;

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1. Hyptis verticillata attenuates dyslipidaemia, oxidative stress and hepato-renal damage in streptozotocin-induced diabetic rats [J] . Ogar Ironya, Egbung Godwin Eneji, Nna Victor Udo, Life sciences . 2019,第期

机译：Hyptis Verticillata在链脲佐菌素诱导的糖尿病大鼠中衰减血脂血症，氧化应激和肝肾损伤
2. Quail (Coturnix japonica) egg yolk bioactive components attenuate streptozotocin-induced testicular damage and oxidative stress in diabetic rats [J] . Oladipo Gideon Oludare, Nlekerem Chidinma Martha, Ibukun Emmanuel Oluwafemi, European journal of nutrition . 2018,第8期

机译：鹌鹑（CoTurnix japonica）蛋黄生物活性组分衰减链脲佐菌素诱导的糖尿病大鼠睾丸损伤和氧化应激
3. Selenium Nanoparticles Attenuate Oxidative Stress and Testicular Damage in Streptozotocin-Induced Diabetic Rats [J] . Dkhil Mohamed A., Zrieq Rafat, Al-Quraishy Saleh, Molecules . 2016,第11期

机译：硒纳米颗粒减轻链脲佐菌素诱导的糖尿病大鼠的氧化应激和睾丸损伤。
4. Probiotics Attenuate Sperm Damage Induced by Oxidative Stress in Rats [C] . Chen Xiaolian, Gong Linzhi, Xu Jianxiong Biomedical Engineering and Biotechnology (iCBEB), 2012 International Conference on . 2012

机译：益生菌减轻大鼠氧化应激引起的精子损伤
5. Examining the protective effects of sesamol on oxidative stress associated blood -brain barrier dysfunction in streptozotocin-induced diabetic rats [D] . VanGilder, Reyna 2009

机译：检查芝麻酚对链脲佐菌素诱导的糖尿病大鼠氧化应激相关的血脑屏障功能障碍的保护作用
6. Selenium Nanoparticles Attenuate Oxidative Stress and Testicular Damage in Streptozotocin-Induced Diabetic Rats [O] . Mohamed A. Dkhil, Rafat Zrieq, Saleh Al-Quraishy, 2016

机译：硒纳米颗粒减轻链脲佐菌素诱导的糖尿病大鼠的氧化应激和睾丸损伤。
7. Thymoquinone, the Most Prominent Constituent of Nigella Sativa, Attenuates Liver Damage in Streptozotocin-Induced Diabetic Rats via Regulation of Oxidative Stress, Inflammation and Cyclooxygenase-2 Protein Expression [O] . Saleh A. Almatroodi, Abdullah M. Alnuqaydan, Mohammed A. Alsahli, 2021

机译：胸腺量，Nigella Sativa最突出的组成，通过调节氧化应激，炎症和环氧化酶-2蛋白表达来抑制链脲佐菌素诱导的糖尿病大鼠的肝损伤

Hyptis verticillata attenuates dyslipidaemia, oxidative stress and hepato-renal damage in streptozotocin-induced diabetic rats

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