Inhibition of liver alanine aminotransferase and aspartate aminotransferase by hesperidin and its aglycone hesperetin: An in vitro and in silico study

Zareei Sara; Boojar Massoud M. A.; Amanlou Massoud

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Inhibition of liver alanine aminotransferase and aspartate aminotransferase by hesperidin and its aglycone hesperetin: An in vitro and in silico study

机译：Husperidin的肝脏丙氨酸氨基转移酶和天冬氨酸氨基转移酶及其糖苷百合素抑制的抑制作用：体外和硅研究

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摘要

Aims: This study aimed to investigate the inhibitory effects of two natural flavonoids, hesperetin (HT) and hesperidin (HD), on two gluconeogenesis enzymes, alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activities and their possible mechanisms of action.

机译：目的：本研究旨在探讨两种天然类异常（Husperetin（HT）和Hosperidin（Hu），在两个葡糖生成酶，丙氨酸氨基转移酶（ALT）和天冬氨酸氨基转移酶（AST）活性的抑制作用及其可能的作用机制。

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来源
《Life sciences》 |2017年第2017期|共7页
作者
Zareei Sara; Boojar Massoud M. A.; Amanlou Massoud;
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作者单位

Kharazmi Univ Dept Biochem Mofateh Ave Tehran Iran;

Kharazmi Univ Dept Biochem Mofateh Ave Tehran Iran;

Univ Tehran Med Sci Fac Pharm Dept Med Chem 16 Azar Ave Tehran Iran;

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原文格式 PDF
正文语种 eng
中图分类医药、卫生;
关键词
Hesperetin; Hesperidin; Alanine aminotransferase; Aspartate aminotransferase; Diabetes; Molecular docking;

机译：Hesperetin;Hesperidin;丙氨酸氨基转移酶;天冬氨酸氨基转移酶;糖尿病;分子对接;

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1. Inhibition of liver alanine aminotransferase and aspartate aminotransferase by hesperidin and its aglycone hesperetin: An in vitro and in silico study [J] . Zareei Sara, Boojar Massoud M. A., Amanlou Massoud Life sciences . 2017,第期

机译：Husperidin的肝脏丙氨酸氨基转移酶和天冬氨酸氨基转移酶及其糖苷百合素抑制的抑制作用：体外和硅研究
2. Association between the alanine aminotransferase/aspartate aminotransferase ratio and new-onset non-alcoholic fatty liver disease in a nonobese Chinese population: a population-based longitudinal study [J] . Yang Zou, Ling Zhong, Chong Hu, Lipids in Health Disease . 2020,第1期

机译：丙氨酸氨基转移酶/天冬氨酸氨基转移酶比和新发病的非酒精性脂肪肝疾病在非同源的中国人群中：基于人群的纵向研究
3. Tissue fractionation studies. 17. Intracellular distribution of monoamine oxidase, aspartate aminotransferase, alanine aminotransferase, d-amino acid oxidase and catalase in rat-liver tissue [J] . C De Duve, H Beaufay, OZ Sellinger, The biochemical journal . 1964,第1期

机译：组织分级研究。 17.单胺氧化酶，天冬氨酸转氨酶，丙氨酸转氨酶，d-氨基酸氧化酶和过氧化氢酶在大鼠肝组织中的细胞内分布
4. Correlation Between Aspartate Aminotransferase/Alanine Transferase Ratio (AST/ALT Ratio) and Stage of Liver Fibrosis in Patients with Chronic Hepatitis [C] . Fitriani Lumongga, Radita Nur Anggraeni Public Health International Conference . 2017

机译：天冬氨酸氨基转移酶/丙氨酸转移酶比（AST / ALT比率）与慢性肝炎患者肝纤维化阶段的相关性
5. Aspartate aminotransferase and aromatic-amino-acid aminotransferase in Escherichia coli. [D] . Orr, Winson M. S. 1977

机译：大肠杆菌中的天冬氨酸转氨酶和芳香族氨基酸转氨酶。
6. Association between the alanine aminotransferase/aspartate aminotransferase ratio and new-onset non-alcoholic fatty liver disease in a nonobese Chinese population: a population-based longitudinal study [O] . Yang Zou, Ling Zhong, Chong Hu, 2020

机译：丙氨酸氨基转移酶/天冬氨酸氨基转移酶比和新发病的非酒精性脂肪肝疾病在非同源的中国人群中：基于人群的纵向研究
7. Association between the alanine aminotransferase/aspartate aminotransferase ratio and new-onset non-alcoholic fatty liver disease in a nonobese Chinese population: a population-based longitudinal study [O] . Yang Zou, Ling Zhong, Chong Hu, 2020

机译：丙氨酸氨基转移酶/天冬氨酸氨基转移酶比和新发病的非酒精性脂肪肝疾病在非同源的中国人群中：基于人群的纵向研究

Inhibition of liver alanine aminotransferase and aspartate aminotransferase by hesperidin and its aglycone hesperetin: An in vitro and in silico study

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