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首页> 外文期刊>RSC Advances >Time-dependent and Pb-dependent antagonism and synergism towards Vibrio qinghaiensis sp.-Q67 within heavy metal mixtures
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Time-dependent and Pb-dependent antagonism and synergism towards Vibrio qinghaiensis sp.-Q67 within heavy metal mixtures

机译：在重金属混合物中的时间依赖和Pb依赖性对抗和朝向vibrio的Qingaeensis sp.-q67的协同作用

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Toxicity interaction has aroused many researchers' interest in the combined toxicity of pollutants. Recently, some published studies have shown that the toxicity of some mixture pollutants is time dependent and well correlated with certain components in the mixture. Therefore, to investigate whether toxicity interaction is affected by the exposure time or certain components, synergism and antagonism within typical environmental contaminants of heavy metal mixtures were analyzed in different exposure times. Herein, three binary and one ternary mixture systems were designed by using three heavy metals: cadmium chloride, lead chloride (Pb) and manganese(II) chloride tetrahydrate (Mn). For each mixture system, five mixture rays with different concentration ratios were arranged by direct equipartition ray design and uniform design ray methods. The toxicities of the three heavy metals and 20 mixture rays towards photobacteria Vibrio qinghaiensis sp.-Q67 (Q67) were determined by the established time-dependent microplate toxicity analysis (t-MTA) in different exposure durations of 0.25, 2, 4, 8 and 12 h. It was shown that the toxicities of three heavy metals (Cd, Pb and Mn) as well as their binary and ternary mixture rays to Q67 were also time dependent, but different metals or mixture rays showed different time characteristics. Surprisingly, some mixture rays exhibited antagonism or synergism with time dependency and the time characteristics varied in different mixture systems. Furthermore, the binary or ternary mixture systems with Pb displayed antagonism, while the Cd-Mn mixture system without Pb exhibited additive action or synergism, which indicated that Pb was probably the causative agent of antagonism produced by mixtures.
机译：毒性相互作用引起了许多研究人员对污染物的综合毒性的兴趣。最近，一些公布的研究表明，一些混合物污染物的毒性是时间依赖性，并且与混合物中的某些组分良好相关。因此，研究毒性相互作用是否受到暴露时间或某些组分的影响，在不同的曝光时间内分析了重金属混合物的典型环境污染物内的协同作用和拮抗作用。在此，通过使用三种重金属设计三个二元和一个三元混合物系统：氯化镉，氯化铅（Pb）和氯化锰四水合物（Mn）。对于每个混合系统，通过直接弯曲光线设计和均匀的设计射线方法排列具有不同浓度比的五种具有不同浓度比的混合射线。通过0.25,2,4,8的不同曝光持续时间，由0.25,2,4,8的不同曝光持续时间确定三种重金属和20次混合物朝向光杆菌的混合物射线朝向光杆菌的滤光射线。（q67）测定和12小时。结果表明，三个重金属（CD，Pb和Mn）以及其二元和三元混合物射线至Q67的毒性也是时间依赖性，但不同的金属或混合射线显示不同的时间特征。令人惊讶的是，一些混合射线显示出对拮抗作用的拮抗作用，并且时间依赖性以及不同混合系统中变化的时间特性。此外，具有PB显示拮抗作用的二元或三元混合物系统，而没有PB的CD-Mn混合系统表明Pb可能是由混合物产生的拮抗作用的致拮抗剂的原因。

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  • 来源
    《RSC Advances》 |2018年第46期|共10页
  • 作者

    Zhang Jin; Ding Ting-Ting; Dong Xin-Qin; Bian Zhi-Qiang;

  • 作者单位

    Anhui Jianzhu Univ Coll Environm &

    Energy Engn Key Lab Water Pollut Control &

    Wastewater Resourc Hefei 230601 Anhui Peoples R China;

    Anhui Jianzhu Univ Coll Environm &

    Energy Engn Key Lab Water Pollut Control &

    Wastewater Resourc Hefei 230601 Anhui Peoples R China;

    Anhui Jianzhu Univ Coll Environm &

    Energy Engn Key Lab Water Pollut Control &

    Wastewater Resourc Hefei 230601 Anhui Peoples R China;

    Anhui Jianzhu Univ Coll Environm &

    Energy Engn Key Lab Water Pollut Control &

    Wastewater Resourc Hefei 230601 Anhui Peoples R China;

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