A simple two-photon turn-on fluorescent probe for the selective detection of cysteine based on a dual PeT/ICT mechanism

Chen Xiani; Xu Hang; Ma Shengnan; Tong Hongjuan; Lou Kaiyan; Wang Wei

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A simple two-photon turn-on fluorescent probe for the selective detection of cysteine based on a dual PeT/ICT mechanism

机译：一种简单的双光子导通荧光探针，用于基于双宠物/ ICT机制的半胱氨酸选择性检测

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Herein, a simple two-photon turn-on fluorescent probe, N-(6-acyl-2-naphthayl)-maleimide (1), based on a dual PeT/ICT quenching mechanism is reported for the highly sensitive and selective detection of cysteine (Cys) over other biothiols. The probe was applied in the two-photon imaging of Cys in cultured HeLa cells, excited by a near-infrared laser at 690 nm.

机译：在此，基于双PET / ICT猝灭机制，报告了一种简单的双光子导通荧光探针，N-（6-酰基-2-萘甲酯）-MaleImide（1），用于对半胱氨酸的高度敏感和选择性检测（Cys）在其他生物醇上。探针应用于培养的HeLa细胞中的Cys的双光子成像，通过近红外激光在690nm处激发。

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来源
《RSC Advances》 |2018年第24期|共5页
作者
Chen Xiani; Xu Hang; Ma Shengnan; Tong Hongjuan; Lou Kaiyan; Wang Wei;
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作者单位

East China Univ Sci &

Technol Shanghai Key Lab New Drug Design Shanghai Key Lab Chem Biol Sch Pharm State Key Lab Bioengn Reactor 130 Meilong Rd Shanghai 200237 Peoples R China;

East China Univ Sci &

Technol Shanghai Key Lab New Drug Design Shanghai Key Lab Chem Biol Sch Pharm State Key Lab Bioengn Reactor 130 Meilong Rd Shanghai 200237 Peoples R China;

East China Univ Sci &

Technol Shanghai Key Lab New Drug Design Shanghai Key Lab Chem Biol Sch Pharm State Key Lab Bioengn Reactor 130 Meilong Rd Shanghai 200237 Peoples R China;

East China Univ Sci &

Technol Shanghai Key Lab New Drug Design Shanghai Key Lab Chem Biol Sch Pharm State Key Lab Bioengn Reactor 130 Meilong Rd Shanghai 200237 Peoples R China;

East China Univ Sci &

Technol Shanghai Key Lab New Drug Design Shanghai Key Lab Chem Biol Sch Pharm State Key Lab Bioengn Reactor 130 Meilong Rd Shanghai 200237 Peoples R China;

East China Univ Sci &

Technol Shanghai Key Lab New Drug Design Shanghai Key Lab Chem Biol Sch Pharm State Key Lab Bioengn Reactor 130 Meilong Rd Shanghai 200237 Peoples R China;

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正文语种 eng
中图分类化学;
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1. A simple two-photon turn-on fluorescent probe for the selective detection of cysteine based on a dual PeT/ICT mechanism [J] . Chen Xiani, Xu Hang, Ma Shengnan, RSC Advances . 2018,第24期

机译：一种简单的双光子导通荧光探针，用于基于双宠物/ ICT机制的半胱氨酸选择性检测
2. A selective fluorescent probe based on bis-Schiff base for "turn-on" detection of Al3+ and cysteine by different mechanisms [J] . Li Yang, Liao Caiyun, Huang Shanshan, RSC Advances . 2016,第30期

机译：基于双席克碱的选择性荧光探针，用于通过不同机制的“开启”检测Al3 +和半胱氨酸的“开启”检测
3. A selective fluorescent probe based on bis-Schiff base for “turn-on” detection of Al3+ and cysteine by different mechanisms [J] . Yang Li, Caiyun Liao, Shanshan Huang, RSC Advances . 2016,第30期

机译：基于双席克碱的选择性荧光探针，用于通过不同机制的“开启”检测Al3 +和半胱氨酸的“开启”检测
4. In vivo quantitative visualization of hypochlorous acid in the liver using a novel selective two-photon fluorescent probe [C] . Haolu Wang, Aparna Jayachandran, Germain Gravot, SPIE biophotonics Australasia . 2016

机译：使用新型选择性双光子荧光探针对肝脏中的次氯酸进行体内定量可视化
5. Proposed Synthetic Route and Molecular Docking Studies of Click-Based Dual Fluorescent Probes for the Ratiometric Detection of G4 DNA [D] . Risley, Victoria Ann. 2018

机译：用于基于比例检测G4 DNA的基于点击的双荧光探针的拟议合成路线和分子对接研究
6. Cyclodextrin-Based Metal-Organic Nanotube as Fluorescent Probe for Selective Turn-On Detection of Hydrogen Sulfide in Living Cells Based on H2S-Involved Coordination Mechanism [O] . Xuelian Xin, Jingxin Wang, Chuanfang Gong, -1

机译：基于H2S参与的配位机制的基于环糊精的金属有机纳米管作为荧光探针选择性开启检测活细胞中的硫化氢
7. Cyclodextrin-Based Metal-Organic Nanotube as Fluorescent Probe for Selective Turn-On Detection of Hydrogen Sulfide in Living Cells Based on H2S-Involved Coordination Mechanism [O] . Xuelian Xin, Jingxin Wang, Chuanfang Gong, 2016

机译：基于环糊精的金属 - 有机纳米管作为荧光探针，用于基于H2S涉及协调机制选择性导通检测活细胞硫化氢的检测

A simple two-photon turn-on fluorescent probe for the selective detection of cysteine based on a dual PeT/ICT mechanism

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