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The highly sensitive determination of serotonin by using gold nanoparticles (Au NPs) with a localized surface plasmon resonance (LSPR) absorption wavelength in the visible region

机译:通过使用金纳米颗粒(Au nps)在可见区域中具有局部表面等离子体共振(LSPR)吸收波长的金纳米颗粒(AU NPS)的高敏感测定

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摘要

The development of improved methods for the synthesis of monodisperse gold nanoparticles (Au NPs) is of high priority because they can be used as substrates for surface-enhanced Raman scattering (SERS) applications relating to biological lipids. Herein, Au NPs have been successfully synthesizedviaa seed-mediated growth method. The LSPR peak is controlledviaadjusting the gold nanoseed component, and different fabrication methods were studied to establish the effect of sonication time on NP size. The simple, facile, and room-temperature method is based on a conventional ultrasonic bath, which leads to ultrasonic energy effects on the size and morphology of the Au NPs. This research offers new opportunities for the production of highly monodispersed spherical Au NPs without the use of a magnetic stirrer method, as evidenced by ultraviolet-visible reflectance spectra and scanning electron microscopy (SEM) analysis. SEM images indicate that the spherical Au NP colloidal particles are stable and reliable, which paves the way for their use as a nanostructured biosensor platform that can be exploited for multiple applications, for example, in materials science, sensing, catalysis, medicine, food safety, biomedicine,etc.The highest enhancement factor that could be achieved in terms of the SERS enhancement activity of these Au NP arrays was determined using 10(-9)M serotonin (5-hydroxytryptamine, 5-HT) as the Raman probe molecules.
机译:的单分散金纳米颗粒的合成(金纳米粒子)的改进的方法的发展是高优先级的,因为它们可以被用作用于表面增强拉曼散射(SERS)与生物脂质应用的基材。在这里,金纳米粒子已成功synthesizedviaa种子介导的生长方法。局域表面等离子体共振峰controlledviaadjusting金nanoseed分量,并且研究了不同的制造方法来建立的声波处理时间对NP尺寸的影响。简单,轻便,并室温方法是基于以往的超声波浴,这导致在金纳米粒子的大小和形态的超声波能量的效果。本研究提供了如由紫外 - 可见反射光谱和扫描电子显微镜(SEM)分析用于生产高度单分散球形金纳米粒子的不使用磁力搅拌器方法的新的机会。 SEM图像表明,球形金纳米粒子胶体粒子稳定可靠,这铺平了道路,他们的纳米结构的生物传感器平台使用,可为多种应用所利用,例如道路,在材料科学,传感,催化,医药,食品安全,生物医药,用10(-9)M血清素(5-羟色胺,5-HT)作为拉曼探针分子中确定可在这些金NP阵列的SERS增强活性方面来实现etc.The最高增强因子。

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  • 来源
    《RSC Advances》 |2020年第51期|共12页
  • 作者单位

    Univ Sci Fac Mat Sci &

    Technol Ho Chi Minh City Vietnam;

    Univ Sci Fac Mat Sci &

    Technol Ho Chi Minh City Vietnam;

    Univ Sci Fac Mat Sci &

    Technol Ho Chi Minh City Vietnam;

    Vietnam Natl Univ Ho Chi Minh City Vietnam;

    Univ Sci Fac Mat Sci &

    Technol Ho Chi Minh City Vietnam;

    Gachon Univ Dept Nanophys Seongnam Si 13120 Gyeonggi Do South Korea;

    Vietnam Natl Univ Ho Chi Minh City Vietnam;

    Duy Tan Univ Inst Fundamental &

    Appl Sci Future Mat &

    Devices Lab Ho Chi Minh City 700000 Vietnam;

    Gachon Univ Dept Ind Environm Engn Coll Ind Environm Engn Seongnam Si 13120 Gyeonggi Do South Korea;

    Univ Sci Fac Mat Sci &

    Technol Ho Chi Minh City Vietnam;

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  • 正文语种 eng
  • 中图分类 化学;
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