• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>RSC Advances >Carboxylato- pillar[6] arene- based fluorescent indicator displacement assays for the recognition of monoamine neurotransmitters
【24h】

Carboxylato- pillar[6] arene- based fluorescent indicator displacement assays for the recognition of monoamine neurotransmitters

机译：羧基柱[6]基于芳烃的荧光指示剂位移测定，用于识别单胺神经递质

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The complexation of three cationic fluorescent dye guests with the anionic host carboxylato- pillar[ 6] arene ( WP6) was investigated by optical and NMR spectroscopy. Among the selected indicators- a stilbazolium dye ( i1) and two naphthalimide derivatives with positively charged ` anchor' groups ( i2 and i3)- i1 gave a large turn- on, i2 and i3 a large turn- off fluorescence response to the complexation. The size selectivity of the complex formation of pillararenes was demonstrated by comparing the binding constants of the complexes of the three indicators with WP6 and its smaller homologue, WP5. The systems WP6$ i1 and WP6$ i2 were tested as indicator displacement assays for the sensing of monoamine neurotransmitters. The WP6$ i1 system functioned as a turn- off, the WP6$ i2 system as a turn- on sensor for neurotransmitters, and both assays showed a good selectivity to histamine over the other neurotransmitter analytes.
机译：通过光学和NMR光谱研究了三种阳离子荧光染料的粘合剂与阴离子宿主羧基柱[6]芳烃（WP6）的络合。 在选定的指标中 - 斯蒂巴唑鎓染料（I1）和具有带正电荷的`锚'基团（I2和I3） - I1的萘酰胺衍生物，对络合产生了大的匝数，I2和I3。 通过将三种指示剂的复合物的结合常数与WP6及其较小的同源物，WP5进行比较，通过比较三种指标的复合物的结合常数来证明复杂形成的尺寸选择性。 系统WP6 $ I1和WP6 $ I2被测试为用于感应单胺神经递质的指标位移测定。 WP6 $ I1系统用作关闭，WP6 $ I2系统作为神经递质的通行证传感器，并且两种测定对其他神经递质分析物的组胺表示良好的选择性。

著录项

  • 来源
    《RSC Advances》 |2019年第29期|共7页
  • 作者

    Paudics Adrien; Kubinyi Miklos; Bitter Istvan; Bojtar Marton;

  • 作者单位

    Budapest Univ Technol &

    Econ Dept Phys Chem &

    Mat Sci H-1521 Budapest Hungary;

    Budapest Univ Technol &

    Econ Dept Phys Chem &

    Mat Sci H-1521 Budapest Hungary;

    Budapest Univ Technol &

    Econ Dept Organ Chem &

    Technol H-1521 Budapest Hungary;

    Budapest Univ Technol &

    Econ Dept Organ Chem &

    Technol H-1521 Budapest Hungary;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 化学;
  • 关键词

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号