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A fast-responsive two-photon fluorescent probe for monitoring endogenous HClO with a large turn-on signal and its application in zebrafish imaging

机译:一种快速响应的双光子荧光探针,用于监测具有大开启信号的内源性HCLO及其在斑马鱼成像中的应用

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摘要

A novel fast-responsive two-photon fluorescent probe NS-ClO was constructed for imaging endogenous HClO in living cells, tissues and fresh zebrafish with a large turn-on signal (about 860 times) and Stokes shift (about 90 nm). The probe NS-ClO for the recognition of HClO in vivo exhibited fast response (about 1 min) and good selectivity; thus, it might be a useful tool to understand the role of HClO in various physiological processes.
机译:构建了一种新型快速响应的双光子荧光探针NS-CLO用于在活细胞,组织和新鲜斑马鱼中成像内源性HCLO,具有大的导通信号(约860次)和斯托克斯偏移(约90nm)。 用于识别体内HCLO的探针NS-CLO表现出快速响应(约1分钟)和良好的选择性; 因此,它可能是理解HCLO在各种生理过程中的作用的有用工具。

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  • 来源
    《RSC Advances》 |2019年第29期|共5页
  • 作者单位

    Qilu Univ Technol Sch Light Ind &

    Engn Shandong Acad Sci Jinan 250353 Shandong Peoples R China;

    Qilu Univ Technol Sch Light Ind &

    Engn Shandong Acad Sci Jinan 250353 Shandong Peoples R China;

    Qilu Univ Technol Sch Light Ind &

    Engn Shandong Acad Sci Jinan 250353 Shandong Peoples R China;

    Qilu Univ Technol Sch Light Ind &

    Engn Shandong Acad Sci Jinan 250353 Shandong Peoples R China;

    Qilu Univ Technol Sch Light Ind &

    Engn Shandong Acad Sci Jinan 250353 Shandong Peoples R China;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 化学;
  • 关键词

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