Double nucleophilic addition to iminomalonate, leading to the synthesis of quaternary alpha-amino diesters and desymmetrization of the products

Shimizu Makoto; Mushika Miki; Mizota Isao; Zhu Yusong

首页> 外文期刊>RSC Advances >Double nucleophilic addition to iminomalonate, leading to the synthesis of quaternary alpha-amino diesters and desymmetrization of the products

【24h】

Double nucleophilic addition to iminomalonate, leading to the synthesis of quaternary alpha-amino diesters and desymmetrization of the products

机译：二核外核酸产物，导致季甲氨基二酯的合成和产品的脱差异化

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Alkylation of iminomalonate with Grignard reagents followed by oxidation and allylation gave symmetrical quaternary alpha-amino diesters in good yields. Subsequent desymmetrization of a diol derivative from these products was conducted via asymmetric carbamylation catalyzed by Cu-Bnbox to give chiral quaternary aminodiol mono-carbamates.

机译：用格氏试剂烷基化与氧化试剂，然后氧化和烯丙基化得到对称的季甲酰基 - 氨基二酯，良好的产率。通过Cu-Bnbox催化的不对称氨基甲酰化通过这些产物进行二醇衍生物的随后去对称化，得到手性季氨基二醇单氨基氨基酯。

著录项

来源
《RSC Advances》 |2019年第40期|共8页
作者
Shimizu Makoto; Mushika Miki; Mizota Isao; Zhu Yusong;
展开▼
作者单位

Nanjing Tech Univ Sch Energy Sci &

Engn Nanjing 211816 Jiangsu Peoples R China;

Mie Univ Grad Sch Engn Dept Chem Mat Tsu Mie 5148507 Japan;

Mie Univ Grad Sch Engn Dept Chem Mat Tsu Mie 5148507 Japan;

Nanjing Tech Univ Sch Energy Sci &

Engn Nanjing 211816 Jiangsu Peoples R China;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类化学;
关键词

相似文献

外文文献
中文文献
专利

1. Double nucleophilic addition to iminomalonate, leading to the synthesis of quaternary alpha-amino diesters and desymmetrization of the products [J] . Shimizu Makoto, Mushika Miki, Mizota Isao, RSC Advances . 2019,第40期

机译：二核外核酸产物，导致季甲氨基二酯的合成和产品的脱差异化
2. Double nucleophilic addition to iminomalonate, leading to the synthesis of quaternary α-amino diesters and desymmetrization of the products [J] . Makoto Shimizu, Miki Mushika, Isao Mizota, RSC Advances . 2019,第40期

机译：亚氨基丙二酸酯的双亲核加成，导致季α-氨基二酯的合成和产物的脱对称化
3. Double nucleophilic addition to iminomalonate, leading to the synthesis of quaternary α-amino diesters and desymmetrization of the products [J] . Makoto Shimizu, Miki Mushika, Isao Mizota, RSC Advances . 2019,第40期

机译：亚氨基丙二酸酯的双亲核加成，导致季α-氨基二酯的合成和产物的脱对称化
4. One-pot 2 ＋ 2 cyclization/nucleophilic addition of o-alkynyl-O-allenyl phenol leading to cyclobutacchromene derivatives [C] . Shohei Ohno, Avena Ramon, Hiromichi Fujioka 日本化学会春季年会講演予稿集 . 2018

机译：一锅2 + 2环化/亲核加入O-炔基-O-苯甲酸苯酚，其导致Cyclobuta C Chrome衍生物
5. Catalytic asymmetric addition reactions leading to carbon-carbon bond formation: Phenyl and alkenyl transfer to aldehydes and alkynylation of alpha-amino ester. [D] . Ji, Jianxin. 2004

机译：催化不对称加成反应，导致形成碳-碳键：苯基和烯基转移至醛类和α-氨基酯的炔基化反应。
6. Nonenzymatic enantioselective synthesis of all-carbon quaternary centers through desymmetrization [O] . Kimberly S. Petersen -1

机译：通过去对称化全碳四元中心的非酶对映选择性合成
7. Double nucleophilic addition to iminomalonate, leading to the synthesis of quaternary α-amino diesters and desymmetrization of the products [O] . Makoto Shimizu, Miki Mushika, Isao Mizota, 2019

机译：二核外核酸产物，导致季α-氨基二酯的合成和产物的脱差异化

Double nucleophilic addition to iminomalonate, leading to the synthesis of quaternary alpha-amino diesters and desymmetrization of the products

摘要

著录项

相似文献

相关主题

期刊订阅