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Suture retention strength of P(LLA-CL) tissue-engineered vascular grafts

机译：P（LLA-CL）组织工程血管移植物的缝合保留强度

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摘要

The suture retention strength of artificial vascular grafts is a key mechanical property that affects the function of the grafts. Different from the conventional method of testing the suture retention strength, this study simulated the actual suturing state of vascular scaffolds approximately and investigated the effect of graft type, graft wall thickness, and number of stitches on the suture retention strength of poly(l-lactide-co-epsilon-caprolactone) P(LLA-CL) vascular grafts. The results showed that the P(LLA-CL) tissue-engineered vascular scaffolds have excellent suture performance and, when the graft wall thickness is greater than 0.24 mm, the suture retention strength will meet the vascular transplantation standard. Under the same conditions, the greater the number of stitches, the more uniform the force of the anastomosis and then the greater the suture retention strength. This experiment provides a more comprehensive and accurate suture retention strength value for the application of P(LLA-CL) tissue engineered vascular grafts, which helps to guide the further optimization of tissue-engineered vascular grafts to meet specific mechanical performance requirements.
机译：人工血管移植物的缝合保留强度是影响移植物功能的关键机械性能。不同于测试缝合潴留强度的传统方法，这项研究模拟了血管支架的实际缝合状态大致并研究了接枝型，移植壁厚度和针脚数对聚（L-丙交酯的缝合轴承件的影响-Co-epsilon-caprolacterone）p（LLA-CL）血管移植物。结果表明，P（LLA-CL）组织工程化的血管支架具有优异的缝合性能，并且当移植壁厚大于0.24mm时，缝合线保持强度将满足血管移植标准。在相同的条件下，缝线的数量越大，吻合的力越均匀，然后缝合滞留强度越大。该实验为P（LLA-CL）组织工程化血管移植物提供了更全面和准确的缝合保留强度值，这有助于引导组织工程化血管移植物的进一步优化，以满足特定的机械性能要求。

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  • 来源
    《RSC Advances》 |2019年第37期|共7页
  • 作者

    Meng Xin; Wang Xiaofeng; Jiang Yongchao; Zhang Bo; Li Kun; Li Qian;

  • 作者单位

    Zhengzhou Univ Natl Ctr Int Res Micronano Molding Technol Sch Mech Sci &

    Engn Zhengzhou Henan Peoples R China;

    Zhengzhou Univ Natl Ctr Int Res Micronano Molding Technol Sch Mech Sci &

    Engn Zhengzhou Henan Peoples R China;

    Zhengzhou Univ Natl Ctr Int Res Micronano Molding Technol Sch Mech Sci &

    Engn Zhengzhou Henan Peoples R China;

    Zhengzhou Univ Natl Ctr Int Res Micronano Molding Technol Sch Mech Sci &

    Engn Zhengzhou Henan Peoples R China;

    Zhengzhou Univ Peoples Hosp Henan Prov Zhengzhou Henan Peoples R China;

    Zhengzhou Univ Natl Ctr Int Res Micronano Molding Technol Sch Mech Sci &

    Engn Zhengzhou Henan Peoples R China;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 化学;
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