Expeditious synthesis and preliminary antimicrobial activity of deflazacort and its precursors

Esposito Anna; De Gregorio Eliana; De Fenza Maria; DAlonzo Daniele; Satawani Anil; Guaragna Annalisa

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Expeditious synthesis and preliminary antimicrobial activity of deflazacort and its precursors

机译：Deflazacort的迅速合成和初步抗菌活性及其前体

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The synthesis of deflazacort (DFZ) and a preliminary evaluation of its microbial activity against the human pathogens Acinetobacter baumannii and Staphylococcus aureus is herein reported. While DFZ is inactive, one of its synthetic precursors showed a strong antibacterial activity against both Gram-negative and -positive bacteria.

机译：本文报道了Deflazacort（DFZ）的合成及其对人病原体的微生物活性的初步评价。报道。虽然DFZ处于非活动状态，但其一种合成前体之一表明对革兰氏阴性和阳性细菌的强抗菌活性。

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来源
《RSC Advances》 |2019年第37期|共6页
作者
Esposito Anna; De Gregorio Eliana; De Fenza Maria; DAlonzo Daniele; Satawani Anil; Guaragna Annalisa;
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作者单位

Univ Napoli Federico II Dept Chem Sci Via Cintia I-80126 Naples Italy;

Dept Mol Med &

Med Biotechnol Via S Pansini 5 I-80131 Naples Italy;

Univ Napoli Federico II Dept Chem Sci Via Cintia I-80126 Naples Italy;

Univ Napoli Federico II Dept Chem Sci Via Cintia I-80126 Naples Italy;

Symbiotec Pharmalab Pvt Ltd Indore Madhya Pradesh India;

Univ Napoli Federico II Dept Chem Sci Via Cintia I-80126 Naples Italy;

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正文语种 eng
中图分类化学;
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1. Expeditious synthesis and preliminary antimicrobial activity of deflazacort and its precursors [J] . Esposito Anna, De Gregorio Eliana, De Fenza Maria, RSC Advances . 2019,第37期

机译：Deflazacort的迅速合成和初步抗菌活性及其前体
2. Expeditious synthesis and preliminary antimicrobial activity of deflazacort and its precursors [J] . Anna Esposito, Eliana De Gregorio, Maria De Fenza, RSC Advances . 2019,第37期

机译：迅速改善合成和初步抗菌活性的deflazacort及其前体。
3. Expeditious synthesis and preliminary antimicrobial activity of deflazacort and its precursors [J] . Anna Esposito, Eliana De Gregorio, Maria De Fenza, RSC Advances . 2019,第37期

机译：迅速改善合成和初步抗菌活性的deflazacort及其前体。
4. Biosynthesis of Siderophore-Peptides, A Class of Potent Antimicrobial Peptides from Enterobacteria, Requires Two Precursors [C] . Gaelle Vassiliadis, Jean Peduzzi, Delphine Destoumieux-Garzon American Peptide Symposium . 2009

机译：生物合成的绵延肽，一类来自细菌的一类有效的抗微生物肽需要两体前体
5. Investigations into the reactivity and catalytic activity of nanoporous aluminosilicates and their synthesis precursors. [D] . Schaffer, Charles L. 2007

机译：纳米多孔硅铝酸盐及其合成前体的反应性和催化活性的研究。
6. An expeditious and environmentally benign synthesis of dispiro-3-phenylpyrrolothiazoles in ACI/EG eutectic mixture and its antioxidant and antimicrobial activities against urinary tract pathogens [O] . Govindasami Periyasami, Karuppiah Ponmurugan, Natarajan Arumugam, 2019

机译：在ACI / EG低共熔混合物中快速环保地合成dispiro-3-苯基吡咯并噻唑及其对尿道病原体的抗氧化和抗菌活性
7. An expeditious and environmentally benign synthesis of dispiro-3-phenylpyrrolothiazoles in ACI/EG eutectic mixture and its antioxidant and antimicrobial activities against urinary tract pathogens [O] . Govindasami Periyasami, Karuppiah Ponmurugan, Natarajan Arumugam, 2019

机译：ACI /例如共晶混合物中的DIAMIRO-3-苯基吡咯噻唑及其对尿路病原体的抗氧化剂和抗微生物活性的迅速和环境良性合成

Expeditious synthesis and preliminary antimicrobial activity of deflazacort and its precursors

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