Temporal and Spatial Changes of mu-Opioid Receptors in the Brain, Spinal Cord and Dorsal Root Ganglion in a Rat Lumbar Disc Herniation Model

Kaneuchi Yoichi; Sekiguchi Miho; Kameda Takuya; Kobayashi Yoshihiro; Konno Shin-ichi

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Temporal and Spatial Changes of mu-Opioid Receptors in the Brain, Spinal Cord and Dorsal Root Ganglion in a Rat Lumbar Disc Herniation Model

机译：大鼠腰椎间盘突出症脑椎间盘突出症脑，脊髓和背根神经节中MU-FOMIOD受体的时间和空间变化

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摘要

Study Design. Controlled, interventional, animal study.

机译：学习规划。受控，介入，动物研究。

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来源
《Spine》 |2019年第2期|共11页
作者
Kaneuchi Yoichi; Sekiguchi Miho; Kameda Takuya; Kobayashi Yoshihiro; Konno Shin-ichi;
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作者单位

Fukushima Med Univ Sch Med Dept Orthopaed Surg 1 Hikarigaoka Fukushima Fukushima 9601295 Japan;

Fukushima Med Univ Sch Med Dept Orthopaed Surg 1 Hikarigaoka Fukushima Fukushima 9601295 Japan;

Fukushima Med Univ Sch Med Dept Orthopaed Surg 1 Hikarigaoka Fukushima Fukushima 9601295 Japan;

Fukushima Med Univ Sch Med Dept Orthopaed Surg 1 Hikarigaoka Fukushima Fukushima 9601295 Japan;

Fukushima Med Univ Sch Med Dept Orthopaed Surg 1 Hikarigaoka Fukushima Fukushima 9601295 Japan;

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原文格式 PDF
正文语种 eng
中图分类骨科学（运动系疾病、矫形外科学）;
关键词
allodynia; brain; caudate putamen; immunohistochemistry; lumbar disc herniation; mu-opioid receptor; neuropathic pain; nucleus accumbens; opioid; periaqueductal gray matter; western blotting;

机译：Allodyodynia;脑;尾部;免疫组织化;腰椎间盘突出;穆阿片类受体;神经性疼痛;核心腺;阿片类药物;PeriaqueCental灰质;Western Blotting;

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专利

1. Temporal and Spatial Changes of mu-Opioid Receptors in the Brain, Spinal Cord and Dorsal Root Ganglion in a Rat Lumbar Disc Herniation Model [J] . Kaneuchi Yoichi, Sekiguchi Miho, Kameda Takuya, Spine . 2019,第2期

机译：大鼠腰椎间盘突出症脑椎间盘突出症脑，脊髓和背根神经节中MU-FOMIOD受体的时间和空间变化
2. Changes in pain behavior and glial activation in the spinal dorsal horn after pulsed radiofrequency current administration to the dorsal root ganglion in a rat model of lumbar disc herniation: Laboratory investigation [J] . ChoH.K., ChoY.W., KimE.H., Journal of Neurosurgery. Spine. . 2013,第2期

机译：腰椎间盘突出症大鼠模型中脉冲射频电流施加到背根神经节后，疼痛行为和脊髓背角神经胶质激活的变化
3. Down-regulation of mu-opioid receptors in rat and monkey dorsal root ganglion neurons and spinal cord after peripheral axotomy. [J] . Zhang X, Bao L, Shi TJ, Neuroscience: An International Journal under the Editorial Direction of IBRO . 1998,第1期

机译：周围轴切术后大鼠和猴背根神经节神经元和脊髓中的μ阿片受体下调。
4. DORSAL ROOT IMPLANT ON LESIONED SPINAL CORD MORPHOLOGIC FINDINGS OF REGENERATION OF SYNAPSES IN THE MAMMALIAN SPINAL CORD-REPAIR AND RECOVERY [C] . C. C. Turbes Annual Rocky Mountain Bioengineering Symposium . 2003

机译：哺乳动物脊髓修复和恢复突变脊髓形态学发现的背根植入物
5. GABAB receptor expression, function, and trafficking in the dorsal horn of the spinal cord and dorsal root ganglia. [D] . Engle, Mitchell Philip. 2007

机译：GABA B受体在脊髓背角和背根神经节中的表达，功能和运输。
6. Bay11-7082 attenuates neuropathic pain via inhibition of nuclear factor-kappa B and nucleotide-binding domain-like receptor protein 3 inflammasome activation in dorsal root ganglions in a rat model of lumbar disc herniation [O] . Ailiang Zhang, Kun Wang, Lianghua Ding, 2017

机译：Bay11-7082通过抑制腰椎间盘突出症大鼠背根神经节中的核因子-κB和核苷酸结合域样受体蛋白3炎性小体活化来减轻神经性疼痛
7. Temporal and Spatial Changes of μ-Opioid Receptors in the Brain, Spinal Cord and Dorsal Root Ganglion in a Rat Lumbar Disc Herniation Model [O] . Yoichi Kaneuchi, Miho Sekiguchi, Takuya Kameda, 2019

机译：大鼠腰椎椎间盘突出症脑椎间盘突出脑，脊髓和背根神经节中μ-ApiOID受体的时间和空间变化

Temporal and Spatial Changes of mu-Opioid Receptors in the Brain, Spinal Cord and Dorsal Root Ganglion in a Rat Lumbar Disc Herniation Model

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