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首页> 外文期刊>Surgical Endoscopy >Persistent and de novo symptoms after cholecystectomy: a systematic review of cholecystectomy effectiveness.
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Persistent and de novo symptoms after cholecystectomy: a systematic review of cholecystectomy effectiveness.

机译：胆囊切除术后持续和缺乏症状：胆囊切除术效应的系统综述。

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Cholecystectomy is the preferred treatment option for symptomatic gallstones, but the exact relationship between cholecystectomies and symptoms still is unclear. This study aimed to assess the effectiveness of elective cholecystectomy for patients with cholecystolithiasis in terms of both persistent and de novo symptoms.A systematic literature search was conducted in Pubmed and Embase. The search included studies comprising patients 18 years of age or older undergoing elective cholecystectomy for symptomatic cholecystolithiasis. The proportions of symptoms after cholecystectomy were calculated and then subdivided into persistent and de novo symptoms.A total of 38 studies reported the presence of postcholecystectomy symptoms. The results showed that upper abdominal pain, the main indication for cholecystectomy in the majority of the patients, mostly disappeared after surgery. However, it persisted in up to 33 % of the patients and arose de novo in up to 14 %. Diarrhea (85 %) and constipation (76 %) were the persistent symptoms most often reported, whereas upper abdominal pain and vomiting were the least often reported. Flatulence (62 %) was the most often reported new symptom. However, large variations in symptoms were found between studies.The review indicates that cholecystectomy often is ineffective with regard to persistent and de novo symptoms. The finding that the types and proportions of persistent symptoms differ from those that arise de novo suggests that this distinction may be useful in predicting which patients would and which would not benefit from a cholecystectomy.
机译：胆囊切除术是对症状胆结石的首选治疗选择，但胆囊切除术和症状之间的确切关系尚不清楚。本研究旨在评估顽固性和DE Novo症状的胆囊岩患者选择性胆囊切除术的有效性。在PubMed和Embase中进行了系统的文献搜索。该搜索包括，包括18岁或以上的患者接受症状胆囊术治疗的患者的患者。计算胆囊切除术后症状的比例，然后细分为持续的，缺乏症状。38项研究总共报告出现后插心切除症状的存在。结果表明，上腹痛，胆囊切除术在大多数患者的主要指示，手术后大多消失。然而，它持续存在高达33％的患者，并达到高达14％的人。腹泻（85％）和便秘（76％）是最经常报道的持续症状，而上腹痛和呕吐是最不报告的。 Flasulence（62％）是最常见的新症状。然而，研究之间存在症状的大变异。评论表明胆囊切除术在持续和缺乏症状方面往往是无效的。发现持续症状的类型和比例不同于诺维科的类型和比例表明这种区别可能在预测哪个患者并且不会从胆囊切除术中受益。

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