• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Surgical Endoscopy >Endoscopic resection of advanced ampullary adenomas: a single-center 14-year retrospective cohort study
【24h】

Endoscopic resection of advanced ampullary adenomas: a single-center 14-year retrospective cohort study

机译：内镜切除晚期安瓿腺瘤：单中心14年的回顾队列队列研究

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

BackgroundEndoscopic ampullectomy has been recognized as a safe and reliable means to resect selective tumors of the ampulla of Vater and is associated with lower morbidity and mortality rates compared to surgical resection. Success rates range from 42 to 92%, with recurrences reported in up to 33%. Studies on endoscopic resection of advanced lesions such as those with intraductal extension of adenoma (IEA) and lateral spreading adenomas (LSA) are limited. We aimed to evaluate the technical success, complications, and recurrence of endoscopic resection of ampullary adenomas, including advanced lesions.MethodsAll patients referred to the Erasmus Medical Center for endoscopic resection of an ampullary lesion were retrospectively identified between 2002 and 2016. Endoscopic success was defined as complete excision of the adenoma, irrespective of the number of attempts, in the absence of recurrence.ResultsWe included 87 patients with a median age of 65years. Of these, 56 patients (64%) had an adenoma confined to the ampulla (ACA), 20 patients (23%) had an LSA, and 11 patients (13%) were treated for an IEA. The median lesion sizes were 24.6mm, 41.4mm, and 16.3mm, respectively (P<0.001). Complications occurred in 22 patients (25.3%), of which hemorrhage was most prevalent (12.6%), followed by perforation (8.1%). Complications were equally divided (P=0.874). The median follow-up duration was 21.1months (12-45.9) for ACA, 14.7months (4.2-34.5) for LSA, and 5.8months (3.7-22.0) for IEA (P=0.051). Endoscopic resection was curative in 87.5% of patients with an ACA, 85% in patients with an LSA, and in only one patient with an IEA (P<0.001). Recurrence occurred in 10 patients (11.5%) (P=0.733).ConclusionEndoscopic ampullectomy is safe and highly successful in selected patients with an adenoma with or without lateral spreading. Outcomes of endoscopic treatment adenomas with an intraductal extension are less favorable and in these cases surgery should be considered.
机译：BackgroundEndoscopic壶腹已被公认为一种安全可靠的方法切除壶腹部的选择性肿瘤与较低的发病率和死亡率相关比较手术切除。成功率的范围从42到92％，与复发在高达33％的报道。正在研究先进病变的内窥镜切除诸如那些具有腺瘤的导管内延伸（IEA）和横向扩展腺瘤（LSA）的限制。我们的目的是评估该技术成功，并发症及壶腹部腺瘤内镜切除复发，包括先进的lesions.MethodsAll患者提到的Erasmus医学中心为壶腹部病变进行回顾性确定的2002年和2016年成功内镜之间的内窥镜切除定义作为腺瘤的完全切除，不论尝试的数量的，在没有recurrence.ResultsWe的包括87例65年的年龄中位数。这些中，56名患者（64％）有局限于壶腹（ACA）的腺瘤，20例（23％）有LSA，和11例（13％）处理的IEA。平均损伤大小为24.6毫米，41.4毫米，和16.3毫米，分别为（P <0.001）。并发症22例（25.3％），其中的出血是最普遍的（12.6％），其次是穿孔（8.1％）。并发症等分（P = 0.874）。平均随访时间是为IEA（P = 0.051）21.1个月（12-45.9），用于ACA，14.7个月（4.2-34.5），用于LSA，和5.8个月（3.7-22.0）。内窥镜切除的患者87.5％是固化剂与ACA，患者的LSA 85％，并且仅在一个与IEA（P <0.001）的患者。复发发生在10名患者（11.5％）（P = 0.733）.ConclusionEndoscopic壶腹是安全的，在选定的患者非常成功的有或没有横向扩展的腺瘤。与导管内延伸内窥镜治疗腺瘤的结果是不太有利的，并在这些情况下，应考虑手术治疗。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号