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首页> 外文期刊>Surgical Endoscopy >Endoscopic plombage with polyglycolic acid sheets and fibrin glue for gastrointestinal fistulas
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Endoscopic plombage with polyglycolic acid sheets and fibrin glue for gastrointestinal fistulas

机译：具有聚乙醇酸片和纤维蛋白胶水的内镜血栓血浆粘液

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摘要

Background and study aimsGastrointestinal (GI) fistulas arise as adverse events of GI surgery and endoscopic treatment as well as secondary to underlying diseases, such as ulceration and pancreatitis. Until a decade ago, they were mainly treated surgically or conservatively. Bioabsorbable polyglycolic acid (PGA) sheets and fibrin glue, which are commonly used in surgical procedures, have also recently been used in endoscopic procedures for the closure of GI defects. However, there have only been few case reports about successful experiences with this approach. There have not been any case-series studies investigating the strengths and weaknesses of such PGA sheet-based treatment. In this study, we evaluated the clinical effectiveness of using PGA sheets to close GI fistulas.Patients and methodsCases in which patients underwent endoscopic filling with PGA sheets and fibrin glue for GI fistulas at Kobe University Hospital between January 2013 and April 2018 were retrospectively reviewed.ResultsA total of 10 cases were enrolled. They included fistulas due to leakage after GI surgery, aortoesophageal/bronchoesophageal fistulas caused by chemoradiotherapy, or severe acute pancreatitis. The fistulas were successfully closed in 7 cases (70%). The unsuccessful cases involved a fistula due to leakage after surgical esophagectomy and bronchoesophageal fistulas due to chemoradiotherapy or severe acute pancreatitis. Unsuccessful treatment was related to fistula epithelization.ConclusionEndoscopic plombage with PGA sheets and fibrin glue could be a promising therapeutic option for GI fistulas.
机译：背景和研究AIMSGASTOINTESTINAL（GI）瘘管是由于GI手术和内镜治疗的不良事件以及额外的疾病，例如溃疡和胰腺炎。直到十年前，它们主要是手术或保守的。最近也用于外科手术中常用于外科手术的生物可吸收的聚乙醇酸（PGA）片和纤维蛋白胶。但是，只有很少有关于这种方法的成功经验的报告。还没有任何病例系列研究调查这种基于PGA片材的治疗的优点和弱点。在这项研究中，我们评估了使用PGA片材关闭GI瘘管的临床效果。回顾性审查了2013年至2018年1月至2018年4月在2013年1月至2018年4月期间用PGA填充的患者和纤维蛋白胶水粘附的患者和纤维蛋白胶水胶。结果共有10例10例。由于胃肠外科，由化学疗法或严重的急性胰腺炎引起的胃肠杆菌/支气管性瘘管，或严重急性胰腺炎术后，它们包括瘘管。瘘管成功关闭7例（70％）。由于化学疗法或严重的急性胰腺炎，外科食管切除术和支气管光学瘘管后，不成功的病例涉及瘘管。不成功的治疗与瘘管上皮有关。与PGA片和纤维蛋白胶的血管型血栓血栓血栓形成可能是GI瘘管的有希望的治疗选择。

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  • 来源
    《Surgical Endoscopy》 |2019年第6期|共7页
  • 作者

    Nakano Yoshiko; Takao Toshitatsu; Morita Yoshinori; Sakaguchi Hiroya; Tanaka Shinwa; Ishida Tsukasa; Toyonaga Takashi; Umegaki Eiji; Kodama Yuzo;

  • 作者单位

    Kobe Univ Grad Sch Med Dept Internal Med Div Gastroenterol Chuo Ku 7-5-2 Kusunoki Cho Kobe;

    Kobe Univ Grad Sch Med Dept Internal Med Div Gastroenterol Chuo Ku 7-5-2 Kusunoki Cho Kobe;

    Kobe Univ Grad Sch Med Dept Internal Med Div Gastroenterol Chuo Ku 7-5-2 Kusunoki Cho Kobe;

    Kobe Univ Grad Sch Med Dept Internal Med Div Gastroenterol Chuo Ku 7-5-2 Kusunoki Cho Kobe;

    Kobe Univ Grad Sch Med Dept Internal Med Div Gastroenterol Chuo Ku 7-5-2 Kusunoki Cho Kobe;

    Kobe Univ Grad Sch Med Dept Internal Med Div Gastroenterol Chuo Ku 7-5-2 Kusunoki Cho Kobe;

    Kobe Univ Hosp Dept Endoscopy Kobe Hyogo Japan;

    Kobe Univ Grad Sch Med Dept Internal Med Div Gastroenterol Chuo Ku 7-5-2 Kusunoki Cho Kobe;

    Kobe Univ Grad Sch Med Dept Internal Med Div Gastroenterol Chuo Ku 7-5-2 Kusunoki Cho Kobe;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 诊断学;
  • 关键词

    Fistula; Polyglycolic acid sheet; Fibrin glue;

    机译：瘘;聚乙醇酸片;纤维蛋白胶水;

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