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Survival benefits of additional surgery after non-curative endoscopic resection in patients with early gastric cancer: a meta-analysis

机译:患有早期胃癌患者的非疗中内镜切除后额外手术的存活益处:META分析

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BackgroundThe survival benefit of additional surgery after non-curative endoscopic resection of early gastric cancer is a matter of debate. This meta-analysis is intended to draw a convincing conclusion on this issue based on data currently available.MethodsA systematic review of PubMed/Medline database was performed from 2010 to 2018 for studies comparing survival outcomes of additional surgery versus simple follow-up after non-curative endoscopic resection for early gastric cancer. Differences between groups were calculated using either the fixed effects model or random effects model.ResultsTen retrospective studies with 4225 patients met the inclusion criteria. Additional surgery significantly provided better 5years overall survival [odds ratios (OR) 3.50, 95% confidence interval (95% CI) 2.89-4.24] and disease-specific survival (OR 3.99, 95% CI 2.50-6.36).ConclusionsAdditional surgery offers survival benefits to patients undergoing non-curative endoscopic resection of early gastric cancer.
机译:术后早期胃癌的非治疗性内镜切除再次手术的背景:生存益处是个见仁见智的问题。此荟萃分析,旨在让人们基于当前available.MethodsA是从2010年执行到2018年考研/ MEDLINE数据库系统的审查比较额外的手术与简单的跟进后非的生存结果的研究数据对这一问题有说服力的结论治疗内镜切除早期胃癌。无论是使用固定效应模型或model.ResultsTen回顾性研究中有4225例患者随机效应符合纳入标准计算组间的差异。显著提供更好的附加手术5年总体存活[比值比(OR)3.50,95%置信区间(95%CI)2.89-4.24]和疾病特异性存活率(OR 3.99,95%CI 2.50-6.36).ConclusionsAdditional手术报价生存利益进行早期胃癌的非治疗性内镜切除的患者。

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