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Benefits of laparoscopic surgery compared to open standard surgery for gastric carcinoma in elderly patients: propensity score-matching analysis

机译:腹腔镜手术的益处与老年患者胃癌的开放标准手术相比:倾向分数匹配分析

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BackgroundLaparoscopic surgery is frequently performed, and laparoscopic gastrectomy (LG) is also widely performed for gastric cancer. Elderly population with gastric cancer has increased in East Asia, including in Japan.MethodsWe examined 1131 patients with gastric cancer who underwent laparoscopic and open standard surgeries (OG). A total of 921 patients of age75years (non-E group) and 210 patients of age75years (E group) underwent surgery for gastric cancer. The mortality, morbidity, and prognosis of LG and OG were compared by propensity score-matched analysis.ResultsMortality and morbidity in the E group were significantly higher than those in the non-E group (p0.05). Propensity score-matching revealed that the incidence of postoperative complications of grade2 in the OG subgroup was significantly higher than that in the LG subgroup in the E group (p0.05). The overall survival rate of the LG subgroup was significantly higher than that of the OG subgroup in both the non-E and E groups (p0.05). The depth of tumor invasion, lymph node metastasis, and the number of dissected lymph nodes were dependent factors for survival in the non-E group, whereas the depth of tumor invasion was the only dependent factor for survival in the E group in the multivariate analysis.ConclusionThe survival rate of patients who underwent LG showed significantly good prognosis in both the non-E and E groups, although the E group patients who underwent OG subgroup showed higher severe complication incidences than those who underwent LG subgroup.
机译:背景皮质镜手术经常进行,腹腔镜胃切除术(LG)也广泛对胃癌进行。胃癌的老年人在东亚增加,包括日本。乙二岛检查了1131例胃癌患者,胃癌接受了腹腔镜和开放标准手术(OG)。共有921名年龄患者75岁(非E群)和210名Agy75年龄(E组)接受胃癌手术。通过倾向分数匹配的分析比较LG和OG的死亡率,发病率和预后。E组中的结果和发病率明显高于非E组(P <0.05)。倾向得分匹配揭示了OG亚组术后2级术后并发症的发生率显着高于E组中LG亚组(P <0.05)。 LG亚组的整体存活率显着高于非E和E组中的OG亚组(P <0.05)。肿瘤侵袭,淋巴结转移的深度和解剖淋巴结的数量是非E群中存活的依赖性因素,而肿瘤侵袭的深度是多变量分析中E组存活的唯一因素结论患者的患者的存活率在非E和E群中表现出明显良好的预后,尽管接受OG亚组的E群患者表现出更高的严重并发症发生率,而不是那些接受LG子组的那些。

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