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Comparison of robotic- and laparoscopic-assisted gastrectomy in advanced gastric cancer: updated short- and long-term results

机译:机器人和腹腔镜辅助胃切除术治疗晚期胃癌的比较:更新短期和长期结果

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摘要

BackgroundEmerging evidence has demonstrated that either laparoscopic-assisted gastrectomy (LAG) or robotic-assisted gastrectomy (RAG) could be adopted as standard treatment for early gastric cancer. However, the long-term survival and recurrence rate after LAG or RAG for locally advanced gastric cancer (AGC) has seldom been reported.MethodsWe retrospectively analyzed the data from 339 patients who underwent LAG and 163 patients who underwent RAG from a prospectively established database in the Chinese People's Liberation Army General Hospital. We compared the short- and long-term oncological outcomes of the RAG group versus the LAG group in the entire cohort, and in a propensity score-matched cohort.ResultsBefore propensity score matching (PSM), the two groups revealed comparable 3-year overall survival rates (OS, RAG vs. LAG: 76.1 vs. 81.7%, p=0.118), and recurrence-free survival rates (RFS, RAG vs. LAG: 73.0 vs. 67.6%, p=0.297). Similar results were obtained in the propensity score-matched cohort; the respective overall survival rates in the propensity score-matched RAG and LAG groups were 76.1 and 79.8% (p=0.552), and the respective RFS rates were 73.0 and 68.7% (p=0.386). After PSM, RAG was still associated with a significantly longer mean operating time (249.4663.26 vs. 232.17 +/- 65.39min, p=0.008) and higher total costs (133.38 +/- 41.62 vs. 95.34 +/- 29.39 10(3) RMB, p0.001) than LAG; the two groups did not significantly differ in other surgical and oncological characteristics.Conclusion Although there were some differences in the outcomes of RAG versus LAG in AGC patients, both RAG and LAG were similar in short-term recovery and long-term oncological outcomes.
机译:背景技术证据表明,腹腔镜辅助胃切除术(滞后)或机器人辅助胃切除术(RAG)可作为早期胃癌的标准治疗采用。然而,落后或抹布局部晚期胃癌(AGC)后的长期存活率很少已经报道.Thodswe回顾性地分析了来自339名接受滞后和163名患者的患者的数据,从目前建立的数据库中接受了RAG的患者中国人民解放军总医院。我们比较了RAG组与整体队列中的LAG组的短期和长期的肿瘤学结果,并在倾向得分匹配cohort.ResultsBefore倾向评分匹配(PSM),两组透露3年总媲美存活率(OS,RAG与LAG:76.1与81.7%,P = 0.118)和无复发的存活率(RFS,RAG与LAG:73.0与67.6%,P = 0.297)。在倾向得分匹配的队列中获得了类似的结果;倾态得分匹配的rag和滞后组中的各个总存活率为76.1和79.8%(p = 0.552),相应的射频率为73.0和68.7%(P = 0.386)。 PSM后,RAG仍然与明显更长的平均工作时间(249.4663.26与232.17 +/- 65.39min,P = 0.008)和较高的总成本(133.38 +/- 41.62 vs. 95.34 +/- 29.39( 3)人民币,P <0.001)比滞后;两组没有显著其他外科和肿瘤characteristics.Conclusion不同虽然有在RAG与在AGC患者LAG的结果有些差异,两者RAG和LAG是在短期恢复和长期肿瘤学结果相似。

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  • 来源
    《Surgical Endoscopy》 |2019年第2期|共7页
  • 作者单位

    Chinese Peoples Liberat Army Gen Hosp Dept Gen Surg Fuxing Rd 28 Beijing 100853 Peoples R China;

    Chinese Peoples Liberat Army Gen Hosp Dept Gen Surg Fuxing Rd 28 Beijing 100853 Peoples R China;

    Chinese Peoples Liberat Army Gen Hosp Dept Gen Surg Fuxing Rd 28 Beijing 100853 Peoples R China;

    Chinese Peoples Liberat Army Gen Hosp Dept Gen Surg Fuxing Rd 28 Beijing 100853 Peoples R China;

    Chinese Peoples Liberat Army Gen Hosp Dept Gen Surg Fuxing Rd 28 Beijing 100853 Peoples R China;

    Chinese Peoples Liberat Army Gen Hosp Dept Gen Surg Fuxing Rd 28 Beijing 100853 Peoples R China;

    Nanjing Gen Hosp Nanjing Mil Command Nanjing 210002 Jiangsu Peoples R China;

    Chinese Peoples Liberat Army Gen Hosp Dept Gen Surg Fuxing Rd 28 Beijing 100853 Peoples R China;

    Chinese Peoples Liberat Army Gen Hosp Dept Gen Surg Fuxing Rd 28 Beijing 100853 Peoples R China;

    Chinese Peoples Liberat Army Gen Hosp Dept Gen Surg Fuxing Rd 28 Beijing 100853 Peoples R China;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 诊断学;
  • 关键词

    Gastric cancer; Robotic-assisted gastrectomy; Laparoscopic-assisted gastrectomy; Clinical outcomes;

    机译:胃癌;机器人辅助胃切除术;腹腔镜辅助胃切除术;临床结果;

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