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首页> 外文期刊>Surgical Endoscopy >Oncological outcome following laparoscopic versus open surgery for cancer in the transverse colon: a nationwide cohort study
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Oncological outcome following laparoscopic versus open surgery for cancer in the transverse colon: a nationwide cohort study

机译：在横向冒号中腹腔镜与癌症的开放手术后的肿瘤结果：全国范围内的队列研究

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Background The literature on transverse colonic cancer resection is sparse. The optimal surgical approach for this disease is thus unknown. This study aimed to examine laparoscopic versus open surgery for transverse colonic cancer. Methods This study was a nationwide, retrospective cohort study of all patients registered with a transverse colonic cancer in Denmark between 2010 and 2013. Data were obtained from the Danish Colorectal Cancer Group, the Danish Pathology Registry, Danish National Patient Registry, and patients’ records. Main outcome measures were surgical resection plane, lymph node yield, and long-term cancer recurrence and survival. Results In total, 357 patients were included. Non-mesocolic resection was more frequent with laparoscopic compared with open resection (adjusted odds ratio 2.44, 95% CI 1.29–4.60, P ?=?0.006). Median number of harvested lymph nodes was higher after open compared with laparoscopic resection (22 versus 19, P ?=?0.03). Non-mesocolic resection (adjusted hazard ratio 2.45, 95% CI 1.25–4.79, P ?=?0.01) and increasing tumor stage ( P ?
机译：背景技术横向结肠癌切除术的文献是稀疏的。因此，这种疾病的最佳手术方法是未知的。本研究旨在检查腹腔镜对横向结肠癌的开放手术。方法本研究是全国性的，回顾性队列的叙述队列的所有患者在2010年和2013年之间向丹麦丹麦癌症中注册的所有患者。从丹麦结直肠癌，丹麦病理登记处，丹麦国家患者登记和患者记录中获得数据。主要结果措施是手术切除平面，淋巴结产量和长期癌症复发和生存。结果总计357名患者。与开放切除相比，腹腔镜（调节的差距2.44,95％CI 1.29-4.60，P≥0.006），腹腔镜比腹腔镜切除术后更频繁。与腹腔镜切除相比，开放后，收获的淋巴结的中位数更高（22与19，p？= 0.03）。非培素切除（调整后危险比2.45,95％CI 1.25-4.79，P？= 0.01）和增加肿瘤阶段（P？<0.001）是与复发相关的因素。癌症复发显着与增加的死亡风险增加（调整后危险比4.32,95％CI 2.75-6.79，P？<0.001）。然而，总体死亡率与手术方法或外科手术平面无关。结论虽然与较低的中核切除术平面和收获的淋巴结率较低，但腹腔镜手术对于横向结肠癌的腹腔镜手术导致了类似的长期结果与开放切除相比。

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