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首页> 外文期刊>Pediatric blood & cancer >Preoperative computed tomography scanning for abdominal neuroblastomas is superior to magnetic resonance imaging for safe surgical planning
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Preoperative computed tomography scanning for abdominal neuroblastomas is superior to magnetic resonance imaging for safe surgical planning

机译：腹部神经细胞瘤的术前计算断层扫描扫描优于磁共振成像，用于安全手术规划

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Abstract Background Cross‐sectional imaging is required to assess disease prior to surgery for neuroblastoma (NBL), and both magnetic resonance imaging (MRI) and computed tomography (CT) scan are considered acceptable. We had concerns that MRI was underestimating disease extent, so from early 2016 we have systematically used MRI and CT before all abdominal NBL resections. The aim of this retrospective study was to establish which imaging modality is more accurate in determining disease extent, particularly after chemotherapy. Methods Abdominal MRI and CT scans for all children with abdominal NBL referred for surgery from January 2016 to February 2018 were retrospectively reviewed to evaluate the extent of disease and the presence of imaging‐defined risk factors (IDRFs). Results Thirty‐one patients were eligible for consideration of surgery post disease reassessment with MRI/MIBG. Twenty‐four of 31 children were included. CT was performed a median of 15 (range, 1–47) days after MRI. MRI underestimated IDRFs compared with CT in 13 of 24 patients (54%). Seventeen of 24 patients underwent surgery, and operative findings had 100% correlation with CT imaging. Notably, there were fundamental changes in management post CT in 6 of 24 patients (25%). CT did not underestimate disease compared with MRI in any patient. Conclusion MRI underestimated the extent of the disease in half of our patients considered for NBL resection. This may be due in part to tumor fibrosis, calcification, and chemotherapy. Preoperative CT scan is the best imaging modality to identify all IDRFs after chemotherapy to ensure safe surgery.
机译：摘要在神经母细胞瘤（NBL）手术前需要横截面成像来评估疾病，并且磁共振成像（MRI）和计算机断层扫描（CT）扫描被认为是可接受的。我们担心MRI低估了疾病程度，因此从2016年初开始，我们在所有腹部NBL切除之前系统地使用MRI和CT。这种回顾性研究的目的是在确定疾病程度，特别是化疗后，确定哪种成像模型更准确。方法回顾性审查2016年1月至2018年2月对手术的腹部MRI和CT扫描的所有腹部NBL的临时审查评估疾病程度和成像定义的风险因素（IDRF）的存在。结果三十一名患者有资格考虑与MRI / MIBG的手术后疾病重新评估。包括31名儿童中的24个。 CT在MRI后的15（范围，1-47）天中的中值进行。 MRI低估了IDRF与24名患者中的13名（54％）的CT相比。 24例患者的患者接受手术，与CT成像有100％的相关性。值得注意的是，在24例患者中的6例中有6例（25％）的CT术后的根本变化。与任何患者的MRI相比，CT没有低估疾病。结论MRI低估了我们考虑过NBL切除患者的一半患者的疾病程度。这可能部分是肿瘤纤维化，钙化和化疗。术前CT扫描是化疗后识别所有IDRF的最佳成像模型，以确保安全手术。

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