...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Pediatrics: Official Publication of the American Academy of Pediatrics >Behavior and Quality of Life at 6 Years for Children With Hypoplastic Left Heart Syndrome
【24h】

Behavior and Quality of Life at 6 Years for Children With Hypoplastic Left Heart Syndrome

机译：Hypoplast左心综合征的儿童6年的行为和生活质量

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

OBJECTIVES: We measured behavioral, quality of life (QoL), and functional status outcomes for 6-year-old children with hypoplastic left heart syndrome enrolled in the Single Ventricle Reconstruction Trial. We sought to compare these outcomes with those in the normative population and to analyze risk factors for worse outcomes within the single-ventricle group. METHODS: Parent-response instruments included the Vineland Adaptive Behavior Scales, Second Edition (Vineland-II) (primary outcome), Behavior Assessment System for Children 2, Pediatric Quality of Life Inventory 4.0, and other measures of QoL and functional status. We compared subjects with those in the normative sample using 1-sample Wilcoxon rank tests and assessed outcome predictors using multivariable regression. RESULTS: Of 325 eligible patients, 250 (77%) participated. Compared with population norms, participants had lower scores on the Vineland-II motor skills domain (90 +/- 17 vs 100 +/- 15; P 2 SDs below the normative mean. On nearly all major domains, more study subjects (3.3%-19.7%) scored outside the normal range than anticipated for the general population. Independent risk factors for lower Vineland-II scores included perioperative extracorporeal membrane oxygenation, male sex, use of regional cerebral perfusion, catheterization after stage 2 operation, visual problems, seizure history, and more complications after 2 years (R-2 = 0.32). Independent predictors of worse Behavior Assessment System for Children 2 (R-2 = 0.07-0.20) and Pediatric Quality of Life Inventory 4.0 (R-2 = 0.17-0.25) domain scores also included sociodemographic factors and measures of morbidity and/or greater course complexity. CONCLUSIONS: At 6 years, children with hypoplastic left heart syndrome had difficulty in areas of adaptive behavior, behavioral symptoms, QoL, and functional status. Principal risks for adverse outcomes include sociodemographic factors and measures of greater course complexity. However, models reveal less than one-third of outcome variance.
机译：目的：我们测量了6岁儿童的行为，生活质量（QOL）和功能状态结果，患有Hymoplastic左心综合征，患有单一的心室重建试验。我们试图将这些结果与规范人口中的这些结果进行比较，并分析单脑室内更糟糕的结果的风险因素。方法：父母响应仪器包括留言自适应行为规模，第二版（Vineland-II）（主要结果），儿童行为评估系统2，生活质量库存4.0，以及其他QOL和功能状况的其他措施。我们将含有1-样品Wilcoxon等级试验和使用多变量回归评估预测器的患者将受试者与规范样品中的受试者进行比较。结果：325名符合条件的患者，参加250名（77％）。与人口规范相比，参与者在Vineland-II运动技能域中的得分较低（90 +/- 17 Vs 100 +/- 15; P 2 SDS低于规范平均值。在几乎所有主要域名，更多的研究科目（3.3％） -19.7％）在正常范围之外得分而不是预期的一般人群。较低的Vineland-II分数的独立危险因素包括围手术化体外膜氧合，男性性别，区域脑灌注，阶段后的导尿率，视觉问题，癫痫发作历史，2年后更加复杂化（R-2 = 0.32）。儿童较差的行为评估系统的独立预测因子2（R-2 = 0.07-0.20）和寿命库存的儿科质量库存4.0（R-2 = 0.17-0.25 ）域名还包括社会渗目因子和发病率和/或更大的课程复杂性。结论：在6年后，Hypoplastic左心综合征的儿童在适应性行为，行为症状，QOL和功能状态。不利结果的主要风险包括社会造影因素和更大课程复杂度的措施。但是，模型显示出不到三分之一的结果方差。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号