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首页> 外文期刊>Current opinion in anaesthesiology >Recent advancements in the treatment of lumbar radicular pain.
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Recent advancements in the treatment of lumbar radicular pain.

机译：腰根神经痛的治疗的最新进展。

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PURPOSE OF REVIEW: Lumbar radicular pain is a common and often difficult condition to treat. Current literature supports the theory that radicular pain is at least in part due to an inflammatory process involving cytokines, including tumor necrosis factor alpha and interleukins. This review summarizes some of the most recent research concerning the use of tumor necrosis factor alpha antagonists and interleukin receptor antagonists in the treatment of lumbar radicular pain. RECENT FINDINGS: Recent studies have shown promising results in the treatment of both acute and chronic lumbar radicular pain with tumor necrosis factor alpha antagonists such as etanercept and infliximab, as well as with interleukin receptor antagonists. SUMMARY: Treatment for lumbar radicular pain has long included epidural steroids to inhibit the inflammatory component of radicular pain. Recent studies have more precisely identified the cytokines responsible for this inflammatory process and indicate that inhibition of these cytokines may offer more specific and effective treatment for lumbar radicular pain.
机译：审查目的：腰根神经痛是一种常见且通常难以治疗的疾病。当前的文献支持这样的理论，即根性疼痛至少部分是由于涉及细胞因子的炎性过程，所述细胞因子包括肿瘤坏死因子α和白介素。这篇综述总结了一些有关肿瘤坏死因子α拮抗剂和白介素受体拮抗剂在治疗腰椎根性疼痛中的最新研究。最近的发现：最近的研究表明，使用肿瘤坏死因子α拮抗剂（如依那西普和英夫利昔单抗）以及白介素受体拮抗剂在治疗急性和慢性腰部神经根痛中均取得了可喜的结果。总结：腰部神经根疼痛的治疗长期以来一直包括硬膜外类固醇，以抑制神经根疼痛的炎症成分。最近的研究更精确地确定了引起该炎性过程的细胞因子，并表明抑制这些细胞因子可能为腰部神经根痛提供更具体有效的治疗方法。

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