Banana Peel Extract Suppressed Prostate Gland Enlargement in Testosterone-Treated Mice

Kiichiro Akamine; Tomoyuki Koyama; Kazunaga Yazawa

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Banana Peel Extract Suppressed Prostate Gland Enlargement in Testosterone-Treated Mice

机译：香蕉皮提取物抑制了睾丸激素治疗小鼠的前列腺增大

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A methanol extract of banana peel (BPEx, 200mg/kg, p.o.) significantly suppressed the regrowth of ventral prostates and seminal vesicles induced by testosterone in castrated mice. Further studies in the androgen-respon-sive LNCaP human prostate cancer cell line showed that BPEx inhibited dose-dependently testosterone-induced cell growth, while the inhibitory activities of BPEx did not appear against dehydrotestosterone-induced cell growth. These results indicate that methanol extract of banana peel can inhibit 5alpha-reductase and might be useful in the treatment of benign prostate hyperplasia.

机译：香蕉皮的甲醇提取物（BPEx，200mg / kg，p.o.）可显着抑制睾丸激素诱导的cast割小鼠腹侧前列腺和精囊的再生。在雄激素反应性LNCaP人前列腺癌细胞系中的进一步研究表明，BPEx抑制剂量依赖性睾丸激素诱导的细胞生长，而BPEx的抑制活性并未表现出对脱氢睾丸激素诱导的细胞生长的抑制作用。这些结果表明，香蕉皮的甲醇提取物可以抑制5α-还原酶，并可能用于治疗良性前列腺增生。

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《Bioscience, Biotechnology, and Biochemistry》 |2009年第9期|共4页
作者
Kiichiro Akamine; Tomoyuki Koyama; Kazunaga Yazawa;
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正文语种 eng
中图分类生物科学;
关键词
suppressive effect on benign prostate hyper-plasia; inhibitor of 5alpha-reductase; banana peel extract; anti-androgen effect; mice;

机译：对前列腺增生的抑制作用;5α-还原酶抑制剂;香蕉皮提取物;抗雄激素作用;小鼠;

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1. Banana Peel Extract Suppressed Prostate Gland Enlargement in Testosterone-Treated Mice [J] . Kiichiro Akamine, Tomoyuki Koyama, Kazunaga Yazawa Bioscience, Biotechnology, and Biochemistry . 2009,第9期

机译：香蕉皮提取物抑制了睾丸激素治疗小鼠的前列腺增大
2. Antidepressant-Like Activity of Banana Peel Extract in Mice | Science Publications [J] . Halijah Hassan, Tan P. Tee American Medical Journal . 2011,第2期

机译：香蕉皮提取物对小鼠的抗抑郁活性科学出版物
3. Re: Vincent Misrai, Enrique Rijo, Kevin C. Zorn, Nicolas Barry-Delongchamps, Aurelien Descazeaud. Waterjet Ablation Therapy for Treating Benign Prostatic Obstruction in Patients with Small- to Medium-size Glands: 12-month Results of the First French Aquablation Clinical Registry. Eur Urol 2019;76:667-75 Surgery for Benign Prostatic Enlargement: Water Keeps Flowing Under the Bridge but Are Things Changing? [J] . Montorsi Francesco, Capogrosso Paolo, Salonia Andrea European urology . 2020,第1期

机译：Re：Vincent Misrai，Enrique Rijo，Kevin C. Zorn，Nicolas Barry-Delongchamps，Aurelien Descazeaud。 Waterjet消融治疗治疗小于中等腺体患者的良性前列腺梗阻：第一个法国水产临床登记处的12个月结果。 EUR UROL 2019; 76：667-75良性前列腺扩大的手术：水不断在桥下流动，但是改变的东西？
4. Antihyperglycemic Activity of Banana (Musa nana Lour.) Peel and Its Active Ingredients in Alloxan-Induced Diabetic Mice [C] . Hongmei Wu, Feng Xu, Junjie Hao, International Conference on Material, Mechanical and Manufacturing Engineering . 2015

机译：香蕉（Musa Nana Lour。）果皮和其活性成分在阿仑泛诱导的糖尿病小鼠中的抗血糖活性
5. Extraction and Partial Purification of α-amylase Produced by Aspergillus niger Cultured on Banana Peel (Musa acumunata) [D] . Magaji, Rabiat Abiola. 2018

机译：香蕉果皮（Musa Acumunata）培养的曲霉患者α-淀粉酶的提取及部分纯化
6. Chemical profiling in vitro antimicrobial and antioxidant activities of pomegranate orange and banana peel-extracts against pathogenic microorganisms [O] . Safynaz Magdy Hanafy, Yasser Mohamed Abd El-Shafea, Waleed Diaeddeen Saleh, 2021

机译：化学分析体外抗菌和抗氧化活性的石榴橙色和香蕉剥离对致病微生物
7. The Radioprotective and Anticancer Effects of Banana Peels Extract on Male Mice [O] . Amaal M. Kamal, Mervat S. Taha, Amr M. Mousa 2019

机译：香蕉皮剥落提取物对雄性小鼠的辐射防护和抗癌作用

Banana Peel Extract Suppressed Prostate Gland Enlargement in Testosterone-Treated Mice

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