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Perioperative renal function and surgical outcome

机译：围手术期肾功能与手术结局

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PURPOSE OF REVIEW: A large proportion of patients undergoing surgery have coexisting chronic kidney disease, placing them at greater risk of postoperative morbidity and mortality. The purpose of this review is to review the recent developments in how renal function is estimated, how this relates to surgical outcomes, and how this has been applied clinically. RECENT FINDINGS: Recent developments in defining chronic kidney disease have coincided with an increased recognition of the prognostic importance of even mild preoperative renal dysfunction and the incorporation of more refined estimates of renal function into one of the most widely used risk prediction scores for cardiac surgery. In addition, several novel markers appear to hold promise as better predictors of perioperative outcome in general and acute kidney injury in particular. SUMMARY: Improved accuracy in defining kidney disease will aid clinicians in identifying higher risk patients, and aid earlier diagnosis of acute kidney injury. Further research is required, specifically on the implications of kidney disease in noncardiac surgical patients, and how defining renal function before and after surgery can aid in preventive strategies.
机译：审查目的：接受手术治疗的患者中有很大一部分患者并存慢性肾脏病，这使他们面临更高的术后发病和死亡风险。这篇综述的目的是回顾一下肾功能如何估计，它与手术结果的关系以及如何在临床上应用这些方面的最新进展。最近的发现：定义慢性肾脏疾病的最新进展与人们对甚至轻度术前肾功能不全的预后重要性的认识日益提高以及将更精细的肾功能评估纳入心脏手术最广泛使用的风险预测评分之一相吻合。此外，几种新的标志物似乎有望更好地预测一般和急性肾损伤围手术期的预后。摘要：定义肾脏疾病的准确性提高将有助于临床医生识别高危患者，并有助于早期诊断急性肾损伤。需要进一步的研究，特别是在非心脏外科手术患者中肾脏疾病的影响，以及在手术前后定义肾脏功能如何有助于预防策略。

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