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首页> 外文期刊>Current opinion in anaesthesiology >Important issues for perioperative systemic antimicrobial prophylaxis in surgery
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Important issues for perioperative systemic antimicrobial prophylaxis in surgery

机译：围手术期全身抗菌药物预防的重要问题

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Purpose of Review: Prevention of surgical site infections is a key issue to patient safety and the success of surgical interventions. Systemic antimicrobial prophylaxis is one important component of a perioperative infection prevention bundle. This review focuses on selected recent developments and important concepts in the field. Recent Findings: Joint guidelines (American Society of Health-System Pharmacists, Infectious Diseases Society of America, Surgical Infection Society, Society for Healthcare Epidemiology of America) for antimicrobial prophylaxis in surgery have been recently revised and updated. Furthermore, European Centre for Disease Prevention and Control has issued a report identifying key factors for success. Important updated fields include the duration of prophylaxis; the selection and dosing of the antimicrobial drug; the precise timing of administration; and common and basic principles, including the implementation of local guidelines and attributing the responsibility of appropriate timing to anaesthesiologists. Additionally, the role of preoperative selective digestive decontamination (SDD) in gastrointestinal surgery receives increasing attention. A major concern of SDD, namely increasing microbial resistance, has not been demonstrated to date. Summary: Most frequently, anaesthesiologists administer perioperative antimicrobial prophylaxis. Identification of core principles and harmonization of protocols should facilitate this task and thus help to improve patient safety and to monitor compliance. However, local and regional epidemiology have to be taken into account in order to establish local protocols.
机译：审查目的：预防手术部位感染是患者安全和手术干预成功与否的关键问题。全身性抗生素预防是围手术期预防感染包的重要组成部分。这篇综述着重于本领域精选的近期发展和重要概念。最新发现：最近修订和更新了有关手术中抗菌药物预防的联合指南（美国卫生系统药剂师学会，美国传染病学会，外科感染学会，美国医疗卫生流行病学会）。此外，欧洲疾病预防控制中心发布了一份报告，确定了成功的关键因素。重要的更新字段包括预防的持续时间;抗菌药物的选择和剂量;确切的施药时间;以及共同的基本原则，包括执行当地指南以及将适当时机的责任归于麻醉医师。此外，术前选择性消化净化（SDD）在胃肠道手术中的作用越来越受到关注。迄今为止，SDD的主要问题，即增加微生物抵抗力，尚未得到证实。摘要：最常见的是，麻醉师对围手术期进行抗菌药物预防。核心原则的确定和方案的统一应有助于完成这项任务，从而有助于提高患者安全性和监测依从性。但是，为了建立本地协议，必须考虑本地和区域流行病学。

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