Translation and post-translational modifications in Plasmodium

Sharma Shobhona; Jarori Gotam K.

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Translation and post-translational modifications in Plasmodium

机译：疟原虫的翻译和翻译后修饰

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Malaria is one of the most important human parasitic diseases in the world, affecting about 400 million people and killing about I million children every year. Our relationship with the malarial parasite has been a long one on the evolutionary scale, and the methods adopted by the parasite to thrive and colonize our bodies are truly fascinating. In order to control the disease, it is of fundamental importance to understand the biology of the parasite. In this review we discuss certain unique features in the parasite translation machinery. We also discuss the various post-translational modifications of Plasmodium proteins, that may result in the modulation of their function.

机译：疟疾是世界上最重要的人类寄生虫病之一，每年影响约4亿人，并杀死约100万儿童。从进化的角度来看，我们与疟疾寄生虫的关系由来已久，并且该寄生虫为our壮和定殖我们的身体而采取的方法确实令人着迷。为了控制该疾病，了解该寄生虫的生物学至关重要。在这篇综述中，我们讨论了寄生虫翻译机制中的某些独特功能。我们还讨论了疟原虫蛋白质的各种翻译后修饰，可能会导致其功能的调节。

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《Current Science: A Fortnightly Journal of Research》 |2012年第5期|共8页
作者
Sharma Shobhona; Jarori Gotam K.;
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正文语种 eng
中图分类自然科学现状及发展;
关键词
Plasmodium; post-translational modifications; ribosomal proteins; translation;

机译：疟原虫;翻译后修饰;核糖体蛋白;翻译;

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3. Overlooked post-translational modifications of proteins in Plasmodium falciparum: N- and O-glycosylation - A Review [J] . Adriane R Todeschini, Cristiana S De Macedo, Jose O Previato, Memórias do Instituto Oswaldo Cruz . 2010,第8期

机译：恶性疟原虫中蛋白质的翻译后修饰被忽略：N-和O-糖基化-综述
4. Overlooked post-translational modifications of proteins in Plasmodium falciparum: N- and O-glycosylation - A Review [J] . Adriane R Todeschini, Cristiana S De Macedo, Jose O Previato, Memórias do Instituto Oswaldo Cruz . 2010,第8期

机译：恶性疟原虫中蛋白质的翻译后修饰被忽略：N-和O-糖基化-综述
5. A comprehensive analysis of protein post-translational modifications, disulfide bonds, mutations, and novel types of modifications [C] . Seungjin Na, Eunok Paek American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2011

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6. Effect of translational and post-translational modifications on actin isoforms. [D] . Demers, Ryan William. 2010

机译：翻译和翻译后修饰对肌动蛋白同工型的影响。
7. Sub-cellular localization and post-translational modifications of the Plasmodium yoelii enolase suggest moonlighting functions [O] . Ipsita Pal-Bhowmick, Hardeep K Vora, Gotam K Jarori 2007

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9. Defining the Role of Post-Translational Modifications in SRC-3-Mediated Repression of mRNA Translation. [R] . Johnson, A. 2012

机译：定义翻译后修饰在sRC-3介导的mRNa翻译抑制中的作用。

Translation and post-translational modifications in Plasmodium

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