...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Bioscience, Biotechnology, and Biochemistry >Downregulated Lipid Metabolism in Differentiated Murine Adipocytes by Procyanidins from Defatted Grape Seed Meal
【24h】

Downregulated Lipid Metabolism in Differentiated Murine Adipocytes by Procyanidins from Defatted Grape Seed Meal

机译：脱脂葡萄籽粕中原花青素下调小鼠脂肪细胞中脂质代谢的下调

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Recent reports have proposed possible anti-obesity mechanisms for antioxidants involving increased energy expenditure, pre-adipocyte differentiation and proliferation, decreased lipogenesis and increased lipolysis, and fat oxidation. The aim of this study was to examine and to confirm the anti-obesity effect of the oligomeric and polymeric procyanidin fractions from defatted grape seeds. The lipid metabolism-related mRNA level in the mouse preadipocytes, 3T3-L1 cells, was determined to evaluate the anti-obesity effect of the phenolic fractions from a grape seed meal. Lipid accumulation was reduced by 19% of the control level by the procyanidin fraction originating from the grape seed meal. Emerging from the effect of the treatment on HSL and LPL mRNA expression, lipolytic enzyme activity was not involved in the anti-obesity effects of CPE and FPP from the defatted grape seed meal. We tested and confirmed in this study the effect of the biological activities of oligomeric and polymeric procyanidins from the defatted grape seed meal. It is suggested from the results of this brief study that further studies would be desirable to focus on the anti-obesity effect of the purified extracts of a defatted grape seed meal.
机译：最近的报告提出了抗氧化剂的可能的抗肥胖机制，包括增加能量消耗，脂肪细胞前分化和增殖，脂肪生成减少和脂解增加以及脂肪氧化。这项研究的目的是检查和确认脱脂葡萄籽中低聚和聚合原花青素馏分的抗肥胖作用。测定小鼠前脂肪细胞3T3-L1细胞中与脂质代谢相关的mRNA水平，以评估葡萄籽粕中酚类成分的抗肥胖作用。源自葡萄籽粉的原花青素部分将脂质蓄积降低了对照组水平的19％。从该处理对HSL和LPL mRNA表达的影响中发现，脂解酶活性不参与脱脂葡萄籽粉中CPE和FPP的抗肥胖作用。我们在这项研究中测试并证实了脱脂葡萄籽粉中低聚和聚合原花青素的生物活性的影响。从该简要研究的结果表明，需要进一步的研究来关注脱脂葡萄籽粉的提纯物的抗肥胖作用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号