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Emerging biosensor platforms for the assessment of water-borne pathogens

机译:新兴的生物传感器平台,用于评估水传播病原体

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摘要

Pathogens are key contaminants in water that are responsible for the generation of various water-borne diseases, and include viruses, fungi, bacteria, and protozoan parasites. The pathogenic effects of these species in water depend on their shape, size, composition, and structure. The resulting water-borne diseases are a serious threat to the environment, including to humans and animals, and are directly responsible for environmental deterioration and pollution. The potential presence of these pathogens requires sensitive, powerful, efficient, and ideally real-time monitoring methods for their reproducible quantification. Conventional methods for pathogen detection mainly rely on time-consuming enrichment steps followed by biochemical identification strategies, which require assay times ranging from 24 h to up to a week. However, in recent years, significant efforts have been made towards the development of biosensing technologies enabling rapid and close-to-real-time detection of water-borne pathogens. This review summarizes recent developments in biosensors and sensing systems based on a variety of transducer technologies for water-quality monitoring, with specific focus on rapid pathogen detection.
机译:病原体是在水中,其负责各种水传播疾病的产生,并包括病毒,真菌,细菌和原生动物寄生虫键污染物。这些物种在水中的致病作用取决于它们的形状,尺寸,组成和结构。由此产生的水性疾病对环境和动物(包括人类和动物)的严重威胁,并直接负责环境恶化和污染。这些病原体的潜在存在需要敏感,强大,有效,理想的实时监测方法,可用于其可重复的量化。用于病原体检测的常规方法主要依赖于耗时的富集步骤,然后依靠生化鉴定策略,需要测定时间从24小时到一周时间。然而,近年来,已经促进了生物传感技术的发展,从而能够快速和近距离实时检测水传播病原体。本综述总结了基于各种换能器技术的生物传感器和传感系统的最新发展,用于水质监测,特别关注快速病原体检测。

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