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首页> 外文期刊>The Chemical Engineer >A Project to Develop and Protect Matthew Duchars and John Challenger describe the plans to design and build a facility that the UK would use for emergency vaccine production
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A Project to Develop and Protect Matthew Duchars and John Challenger describe the plans to design and build a facility that the UK would use for emergency vaccine production

机译:开发和保护马修Duchars和John Challenger的项目描述了设计和建造英国将用于应急疫苗生产的设施的计划

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摘要

WITH the sudden appearance of the Covid-19 virus and its impact on practically every nation in the world,the planned development of the Vaccines Manufacturing and Innovation Centre(VMIC)has now become a project of immediate national importance for the United Kingdom.Before describing the development of the new facility,which is now at an advanced stage of design,it is perhaps worthwhile providing a little of the recent history which in some respects mirrored VMIC's formation.During the 1970s,Glaxo and the Wellcome Foundation were two of the major suppliers of vaccines to the NHS but they were increasingly experiencing poor returns on the manufacture of many of the vaccines that formed the backbone of the UK's national child vaccination programme.This inevitably led to decreasing investment in manufacturing facilities which led to an increasing pressure by the then Medicines Inspectorate(the forerunner of today's Medicines and Healthcare products Regulatory Agency)to update them,in order to meet their requirements for current good manufacturing practice.
机译:随着Covid-19病毒的突然外观及其对世界各地的影响,疫苗制造和创新中心(VMIC)的计划开发现已成为英国立即的国家重要性。新设施的开发现在处于一个先进的设计阶段,也许值得提供近期历史的一点,这在某些方面的镜像VMIC的形成。20世纪70年代,Glaxo和Wellcome基金会有两个主要疫苗的供应商对NHS越来越多地体验较差的回报,这些疫苗的许多疫苗的返回,这些疫苗形成了英国国家儿童疫苗接种计划的骨干。这不可避免地导致对制造工具的投资降低,这导致了增加压力然后药物监督者(当今药物和医疗保健制品监管机构的先行者)以orde更新r满足他们对当前良好制造实践的要求。

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